CAS: 63069-50-1; 4-Amino-3-Fluorobenzonitrile

上下游产品

CAS号29632-74-4 2-氟-4-碘苯胺 | CAS号544-92-3 氰化亚铜 | CAS号557-21-1 氰化锌 | CAS号367-24-8 4-溴-2-氟苯胺 | CAS号364082-48-4 3-fluoro-4-[(4-... | CAS号105-56-6 氰乙酸乙酯 | CAS号133059-44-6 4-溴-3-氟苯腈 | CAS号849353-46-4 4-氨基-3-氟-5-碘苯甲腈

4-溴-2-氟苯胺置于cucn体系中,用 (2S)-N-Methyl-1-Phenylpropan-2-Amine Hydrate 作为反应溶剂,化学反应生成 3-氟-4-氨基苯腈
参考文献:1,3-Dioxane Derivatives,Methods Of Preparation And Liquid Crystal
标题:1,3-Dioxane Derivatives,Methods Of Preparation And Liquid Crystal
摘要:以一般式表示的直链烷基为1至10个碳原子的烷基环己烷衍生物为:##str1## 其中r是1至10个碳原子的线性烷基,A是一个单共价键或一个--Ch.Sub.2 Ch.Sub.2--基团,X为f或cn,如果x为cn,则y为f,如果x为f,则y为h或f,环己烷环和1,3-二氧杂环丙烷环为反式异构体.1,3-二氧杂环丙烷衍生物具有较大的正介电常数各向异性(δε),较小的双折射(δn),并且与其他液晶化合物具有非常好的相容性.这些二氧杂环丙烷衍生物可以包含在液晶组合物中,用于改善具有低阈值电压,低驱动电压和宽视角的显示装置.

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-9751874-B2
优先权日:2014-12-17
标题:Hydroxy containing FXR (NR1H4) modulating compounds
发明人：GEGE CHRISTIAN; KINZEL OLAF; KREMOSER CLAUS; SCHMITT AARON C
权利人:GILEAD SCIENCES INC
摘要:The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

专利号:US-9932332-B2
优先权日:2016-06-13
标 题:FXR (NR1H4) modulating compounds
发明人：GEGE CHRISTIAN
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

专利号:US-2019152896-A1
优先权日:2016-07-27
标题 :Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts