CAS: 57018-52-7; 1-Tert-Butoxy-2-Propanol

该化合物是第三级乙醚-酒精化合物,其独特的结构特征是,结合了三丁基乙醇组和二级氢氧基功能.该化合物因其稳定性和溶性而具有价值,适合用作有机合成和特殊化学应用的中间体.三丁氧混合物会增强消毒保护,而氢氧基组则为进一步衍生提供回动性.其平衡的极地性允许与极地溶剂和非极地溶剂兼容,便于其在需要受控再活性的配方中使用.该化合物的界定明确结构确保合成工艺的一致性,特别是在精确分子设计至关重要的制药和精细化学品中.

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4254-14-2 4254-15-3 57-55-6

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CAS号64-17-5 乙醇 | CAS号67-63-0 异丙醇 | CAS号75-56-9 环氧丙烷 | CAS号75-65-0 叔丁醇 | CAS号1343-93-7 磷钨酸 | CAS号57-55-6 丙二醇 | CAS号115-11-7 2-甲基丙烯 | CAS号7580-85-0 乙二醇单叔丁醚 | CAS号28047-97-4 tert-butoxyacet... | CAS号75-16-1 甲基溴化镁 | CAS号28047-99-6 1-[(2-methylpro... | CAS号136579-69-6 (R)-1-tert-buto... | CAS号136656-76-3 (2S)-1-叔丁氧基-2-丙醇

合成工艺路线路线简述

    📜乙二醇单叔丁醚置于2-碘酰基苯甲酸体系中,用 乙醚,乙酸乙酯 作为反应溶剂,化学反应生成 1-叔丁氧基-2-丙醇
    参考文献:钯催化不对称四元立体中心形成
    标题:钯催化不对称四元立体中心形成
    摘要:通过将芳基硼酸共轭加成到各种β,β-二取代的碳环,杂环和无环烯酮上,提出了一种有效的钯催化剂,用于形成苄基季立体中心.该催化剂易于由pdcl 2,Phbox和agsbf 6制备,并以高达99%的对映体过量提供产物.基于此策略,仅需两个步骤即可制备(-)-α-Cuparenone.
    DOI:10.1002/chem.201200694

    海关参考信息

    专利信息


    专利号:US-2024383831-A1
    优先权日:2021-10-07
    标 题 :Alkoxylation of cannabidiol and other cannabinoids
    发明人:LAHASKY SAMUEL; SHARP KIP DOUGLAS; SLIKTA ALBERTO; PRESTRIDGE BRITNEY HEBERT; BARKER EMILY MATTHEWS; RICHARDSON RYAN
    权利人:INDORAMA VENTURES OXIDES LLC
    摘要:The present disclosure generally relates to the synthesis of an alkoxylated cannabinoid using a double metal cyanide (DMC) catalyst. This procedure affords a novel process for preparing water-dispersible and water-soluble versions of cannabidiol (CBD) and other cannabinoids in high yields through mild reaction conditions.

    专利号:US-5043484-A
    优先权日:1990-02-09
    标 题 :Synthesis of hydroxyl-terminated polybutadienes using glycol ether solvents
    发明人:KNIFTON JOHN F; MARQUIS EDWARD T
    权利人:TEXACO CHEMICAL
    摘要:Disclosed is an improvement in a process for polymerizing 1,3-butadiene selectively to form relatively low molecular weight hydroxyl-terminated polybutadiene oligomers in the presence of an aqueous solution of hydrogen peroxide which comprises the use of a glycol ether solvent to produce butadiene oligomers having a high degree of OH functionality and suppression of formation of solid or gel-type insoluble rubber by-products.

    专利号:US-5637757-A
    优先权日:1995-04-11
    标 题 :One-pot synthesis of ring-brominated benzoate compounds
    发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
    权利人:GREAT LAKES CHEMICAL CORP
    摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

    专利号:US-5349110-A
    优先权日:1990-08-20
    标题 :Synthesis of low molecular weight glycol ethers from oxiranes plus olefins
    发明人:KNIFTON JOHN F
    权利人:TEXACO CHEMICAL
    摘要:Disclosed is a process for preparation of monoalkyl ethers by reacting low molecular weight olefins and the corresponding oxiranes, in the presence of a catalyst comprising an acidic heterogeneous or homogeneous catalyst, generally represented by the equation: ##STR1## where R, R', R' may be hydrogen or an alkyl radical.

    专利号:US-8946466-B2
    优先权日:2010-05-18
    标 题 :Method for producing polyether carbonate polyols
    发明人:Gürtler Christoph; Hofmann Jörg; WOLF AUREL; GRASSER STEFAN
    权利人:Gürtler Christoph; Hofmann Jörg; WOLF AUREL; GRASSER STEFAN; BAYER IP GMBH
    摘要:The present invention relates to a process for the preparation of polyether carbonate polyols from one or more H-functional starter substances, one or more alkylene oxides and carbon dioxide in the presence of at least one double metal cyanide catalyst, wherein the cyanide-free metal salt, the metal cyanide salt or both the mentioned salts used for the preparation of the double metal cyanide catalyst contain(s) from 0.3 to 1.8 mol base equivalents (based on 1 mol of the metal cyanide salt used for the synthesis of the catalyst) of alkaline metal hydroxide, metal carbonate and/or metal oxide.

    专利号:US-12036300-B2
    优先权日:2021-03-31
    标题:Methods and compositions for improving skin
    发明人:LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
    权利人:OREAL
    摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s00216-010-3487-0
    摘要:Tomicic C, Berode M. Sensitive headspace gas chromatography analysis of free and conjugated 1-methoxy-2-propanol in urine. Analytical and Bioanalytical Chemistry. 2010 Feb 13;396(7):2709–14. doi: 10.1007/s00216-010-3487-0.
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