CAS: 57-06-7; Allyl Isothiocyanate

该化合物是紫色的,无色的黄液,主要以其独特的芥子气味和口味闻而闻名,是来自在十字架蔬菜(如芥子酱和黄黄菜)中发现的甘蓝酸盐水解的有机化合物.AITC具有很强的刺激性,特别是对眼睛和呼吸系统而言,并被归类为潜在的皮肤敏化剂.该化合物具有C4H5NS分子分子配方,具有硫氰酸盐功能组,有助于其再活性和生物活动.Allyl 异硫氰酸盐具有抗微生物酸性,并已研究其潜在的健康惠益,包括抗癌效应.它通常用作食品的调味剂和农业的天然杀虫剂.由于它的挥发性,应该谨慎处理,并且应当采取适当的安全措施避免接触.

结构式图片

MSDS等安全信息

欧盟法规

REACH注册ECHA物质ECHA物质化妆品禁用物质清单C&L通报欧盟生物杀灭剂法规欧盟《生物杀灭剂法规》REACH预注册

上下游产品

CAS号111915-68-5 2-(prop-2-enylc... | CAS号111915-66-3 1-[2,3-dihydrox... | CAS号111915-67-4 1-[2-(5-methoxy... | CAS号592-88-1 二烯丙基硫醚 | CAS号333-20-0 硫氰酸钾 | CAS号74-90-8 氢氰酸 | CAS号463-56-9 硫氰酸 | CAS号557-40-4 烯丙基醚 | CAS号107-11-9 丙烯胺 | CAS号3766-55-0 4-丙烯基硫代氨基脲

合成工艺路线路线简述

    Diethyl 1-[(Prop-2-En-1-Ylcarbamothioyl)Sulfanyl]Hydrazine-1,2-Dicarboxylate 以85%的收率获得产物天然芥菜籽油
    参考文献:使用偶氮二羧酸二烷基酯合成新型二硫代氨基甲酸酯和黄原酸酯:Sn键的形成
    标题:使用偶氮二羧酸二烷基酯合成新型二硫代氨基甲酸酯和黄原酸酯:Sn键的形成
    摘要:通过在温和且无催化剂的条件下原位反应生成的二硫代氨基甲酸或黄原酸酯与偶氮二羧酸二烷基酯的反应,开发了一种用于合成一类新型二硫代氨基甲酸酯或黄原酸酯的单锅三组分途径.该反应的特点是范围广,效率高和直接的分离方案.在制备对称和不对称的硫脲,异硫氰酸酯和硫代氨基甲酸酯时,证明了二硫代氨基甲酸酯和黄原酸酯的合成效用.
    DOI:10.1016/j.Tet.2018.02.049

    海关参考信息

    专利信息


    专利号:US-8618281-B2
    优先权日:2006-01-03
    标 题 :Geometric synthesis of porphyrin rods
    发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D
    权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE
    摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.

    专利号:US-7718833-B2
    优先权日:2007-11-02
    标 题:Purification of glycerin obtained as a bioproduct from the transesterification of triglycerides in the synthesis of biofuel
    发明人:POTTHAST RAINER; CHUNG CHI PING; MATHUR INDRESH
    权利人:JOHANN HALTERMANN LTD
    摘要:Methods for purifying glycerin contaminated with one or more lower boiling alcohols such as methanol, ethanol, straight, branched or cyclic C3-C6 alcohols, and the like. The methods are particularly useful for purifying crude glycerin phases recovered from the synthesis of biofuels. The present invention uses distillation techniques to strip alcohol contaminants from glycerin. In contrast to conventional methods that carry out distillation either under substantially anhydrous or very wet conditions, the present invention carries out distillation in the presence of a limited amount of water, e.g., from about 0.8 to about 5 parts by weight of water per 100 parts by weight of contaminated glycerin to be purified.

    专利号:US-8147883-B1
    优先权日:1999-09-22
    标题:Use of a plant oil product as an agent for increasing the synthesis of skin lipids
    发明人:MSIKA PHILIPPE; PICCIRILLI ANTOINE
    权利人:MSIKA PHILIPPE; PICCIRILLI ANTOINE; EXPANSCIENCE LAB
    摘要:The invention concerns the use of at least a vegetable oil product selected among the group consisting of vegetable oil oleic distillates, vegetable oil unsaponifiable matters, vegetable oil furan lipids and mixtures thereof, as agents for increasing skin lipid synthesis, in particular lipids of the epidermal skin barrier, in or for preparing a composition containing a pharmaceutically or dermatologically acceptable medium. The use enables to prevent and/or treat deterioration of the skin barrier (dry skin, skin subjected to actinic radiation, ichthyosis, acne, xerosis, atopic dermatitis, sensitive skin, chafing and reactive skin, itching and the like).

    专利号:US-9611352-B2
    优先权日:2014-09-17
    标 题:Synthesis and molecular weight control of aliphatic polyester diols
    发明人:NARINE SURESH; LI SHAOJUN; JOSE JESMY; SHETRANJIWALLA SHEGUFTA; BOUZIDI LAZIZ
    权利人:UNIV TRENT
    摘要:The synthesis of certain polyester diols (PEDs) is disclosed. This application also discloses the purification and polymerization kinetics of lipid based PEDs. Molecular weight and distribution controls were achieved by initial and induced stoichiometric imbalance and optimization of the purification protocol. Thermal degradation and thermal transition behavior of the PEDs were also investigated by TGA and DSC.

    专利号:US-2003153783-A1
    优先权日:1999-06-30
    标题:Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid
    发明人:GIANNESSI FABIO; DELL UOMO NATALINA; TINTI MARIA ORNELLA; DE ANGELIS FRANCESCO
    权利人:SIGMA TAU IND FARMACEUTI
    摘要:A process is described for the preparation of R or S aminocarnitine, R or S phosphonium aminocarnitine and R and S 3,4 diaminobutanoic acid, and their derivatives with the following formula: n n n where Y is as described in the attached description, starting from aspartic acid with the same configuration as the desired compounds. This process is advantageous from the industrial point of view in terms of the type of reactants used, the reduced volumes of solvents and the possibility of avoiding purification of the intermediate products.

    专利号:US-2024010511-A1
    优先权日:2019-05-02
    标 题 :Methods and compositions for synthesis of phosphor and its incorporation in a polymer matrix for light conversion
    发明人:SAHI SUNIL
    权利人:SOLGO INC; SOLGRO INC
    摘要:The invention relates to methods and compositions for synthesizing a phosphor and preparing a surface-modified phosphor comprising a phosphor, a silica, and a silane, and articles comprising same. The invention also relates to a method of dispersion of the disclosed surface-modified phosphor with a blue emitting agent in a polymer matrix and uses thereof.
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    主要参考文献


    1: Agrawal SS, Yallatikar T, Gurjar P. Reversed-phase high-performance liquid chromatographic method development and validation for allyl isothiocyanate estimation in phytosomes of Brassica nigra extract. J Adv Pharm Technol Res. 2019 Jul-Sep;10(3):126-131. doi: 10.4103/japtr.JAPTR_382_18.
    2: Miyano K, Shiraishi S, Minami K, Sudo Y, Suzuki M, Yokoyama T, Terawaki K, Nonaka M, Murata H, Higami Y, Uezono Y. Carboplatin Enhances the Activity of Human Transient Receptor Potential Ankyrin 1 through the Cyclic AMP-Protein Kinase A-A-Kinase Anchoring Protein (AKAP) Pathways. Int J Mol Sci. 2019 Jul 3;20(13). pii: E3271. doi: 10.3390/ijms20133271. doi: 10.1186/s12931-019-1077-z.
    4: Andrei SR, Ghosh M, Sinharoy P, Damron DS. Stimulation of TRPA1 attenuates ischemia-induced cardiomyocyte cell death through an eNOS-mediated mechanism. Channels (Austin). 2019 Dec;13(1):192-206. doi: 10.1080/19336950.2019.1623591.
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