CAS: 55506-37-1; 5-Chlorothiazol-2-Amine Hydrochloride

该化合物是一种化学化合物,其特点是含有氮和硫磺原子的硫酸盐环状结构,该化合物通常作为盐酸盐出现,其溶解性在水中增强,并适合医药和生物化学的各种应用;硫酸盐环的5位置上存在氯原子,有助于其再活性和潜在的生物活动;作为矿产品,它可能表现出诸如基本性和形成氢结的能力等特性,从而影响其在生物系统中的相互作用;该化合物经常受到研究,以了解其在医药化学中的潜在用途,特别是在开发抗微生物或抗癌剂方面的潜在用途;应当与许多化学物质一样,由于潜在的毒性或再活性,遵守安全和处理预防措施;

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欧盟法规

ECHA物质C&L通报REACH预注册

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    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Aldo Andreani, Et Al. Effects Of New Ubiquinone-Imidazo[2,1-B]Thiazoles On Mitochondrial Complex I (Nadh-Ubiquinone Reductase) And On Mitochondrial Permeability Transition Pore. Bioorg Med Chem. 2004 Nov 1;12(21):5525-32.

    合成参考文献


    摘要:Compound: 2-Thiazolamine, 5-chloro-, hydrochloride (1:1)
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