专利号:US-9085550-B2 优先权日:2005-01-21 标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands 发明人:FORMAN BARRY; YU DONNA 权利人:FORMAN BARRY; YU DONNA; HOPE CITY 摘要:Estrogen-Related Receptor (ERR) modulating compounds and methods for synthesis of said compounds are described.
专利号:US-6271391-B1 优先权日:1998-03-13 标题 :Hydrazide fixed to a resin and derivatives thereof, and a method for synthesizing pyrazolones in solid phase 发明人:KOBAYASHI SHU; OYAMADA HIDEKAZU 权利人:JAPAN SCIENCE & TECH CORP 摘要:Hydrazide fixed to a resin represented by the following formula: n n n P—Q—CO—NH—NH 2   (I) n n n where P represents a main chain of a resin polymer and Q represents a hydrocarbon side chain optionally having a substituent which may be bonded via a heteroatom, and a hydrazone derived therefrom and fixed to a resin n n n P—Q—CO—NH—Nâ•?CH—R 1   (II) n n n are provided, and solid phase synthesis of pyrazolone is conducted using the same, thereby enabling synthesis of pyrazolones by the application of the Mannich type reaction based on the solid phase synthesis and efficient construction of libraries for various kinds of them.
专利号:US-8981092-B2 优先权日:2008-09-19 标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity 发明人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO 权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL 摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
专利号:US-2006189825-A1 优先权日:2005-01-21 标题:Ligands for estrogen related receptors and methods for synthesis of said ligands
专利号:US-2022325053-A1 优先权日:2019-08-13 标题:Method for the synthesis of a two-dimensional or quasi-two-dimensional polymer film, the two-dimensional or quasi-two-dimensional polymer film and the use
专利号:US-2013131340-A1 优先权日:2005-01-21 标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands