CAS: 32741-05-2; 2-Isobutylthiophene

上下游产品

2-methyl-1-thiophen-2-yl-propan-1-one thiophene Isobutyl iodide Isobutyl bromide 1-(5-isobutylthiophen-2-yl)ethanone 5-isobutylthiophene-2-carbaldehyde 5-isobutyl-thiophene-2-carboxylic acid 5-isobutylthiophene-2-sulfonamide

📜2-甲基-1-噻吩-2-丙烷-1-酮置于氢氧化钾,肼体系中,用 二乙二醇 用作溶剂,化学反应 3.0H,以61%的收率获得2-异丁基噻吩
参考文献:New Fbpase Inhibitors For Diabetes
标题:New Fbpase Inhibitors For Diabetes
摘要:式的化合物,以及其药学上可接受的盐和酯,其中r1至r3具有申请中给定的含义,并可用于制成药物组合物.

专利信息

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-11685712-B2
优先权日:2019-12-30
标 题 :Synthesis of monofunctional thiuram accelerator
发明人：SPILKER THOMAS FRANKLIN; Jin ji yang; FEHER FRANK J
权利人:GOODYEAR TIRE & RUBBER
摘要:The present invention provides a route for synthesizing monofunctional thiuram compounds that is safe, environmentally friendly, and cost effective. This method specifically involves synthesizing a monofunctional thiuram by (1) reacting a tetraorganylthiuram disulfide with an organyl mercaptan to produce the monofunctional thiuram and a dithiocarbamate metal salt or a dithiocarbamate metalloid salt under basic conditions, (2) separating the monofunctional thiuram in an organic phase from the dithiocarbamate metal salt or the dithiocarbamate metalloid salt in an aqueous phase, and (3) recovering the monofunctional thiuram from the aqueous phase. The monofunctional thiuram compounds made in accordance with this invention are of particular value as accelerators for use in the vulcanization of rubber. The use of these monofunctional thiuram compounds as accelerators provides good cure rates and as well as good scorch safety.

专利号:US-8921583-B2
优先权日:2007-10-04
标题:Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
发明人：PHIASIVONGSA PASIT; SEHL LOUIS C; FULLER WILLIAM DEAN; LAIDIG GUY J
权利人:ONYX THERAPEUTICS INC
摘要:The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.

专利号:US-2005214310-A1
优先权日:2004-01-23
标 题 :Melphalan prodrugs
发明人：TOKI BRIAN E; SENTER PETER D
权利人:SEATTLE GENETICS INC
摘要:Shown and described are the synthesis of more potent forms of C-Mel, a prodrug used in Antibody-Directed Enzyme Prodrug Therapy, that releases the clinically used anticancer alkylating agent melphalan extracellularly. Shown and described are the synthesis of a variety of melphalan analogues with the intention to promote facile intracellular drug access. Esters, amides, and peptides of melphalan are shown. Cephalosporin prodrugs of the most interesting melphalan derivatives were synthesized and evaluated for potency, toxicity, therapeutic window, plasma stability, and solubility.

专利号:US-2429575-A
优先权日:1944-09-16
标 题:Synthesis of branched chain hydrocarbons
发明人：APPLEBY WALTER G; LOVELL LAWRENCE L; LOVE MARK P L
权利人:SHELL DEV

专利号:US-2023029068-A1
优先权日:2019-12-30
标题:Synthesis of monofunctional thiuram accelerator