CAS: 15263-20-4; Tert-Butyl (1,3-Dioxoisoindolin-2-yl) Carbonate

相似化合物

84379-72-6 17720-64-8 1631179-23-1

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-7745626-B2
优先权日:2002-03-29
标 题 :Stereoselective alkylation of chiral 2-methyl-4-protected piperazines
发明人：WU WENXUE; LIAO HONGBIAO; TSAI DAVID J; ANDREWS DAVID R; GALA DINESH; LEE GARY M; SCHWARTZ MARTIN LAWRENCE; MCALLISTER TIMOTHY L; FU XIAOYONG; MALONEY DONAL; THIRUVENGADAM TIRUVETTIPURAM K; TANN CHOU-HANG
权利人:SCHERING CORP
摘要:In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process:

专利号:US-4631211-A
优先权日:1985-03-25
标题 :Means for sequential solid phase organic synthesis and methods using the same
发明人：HOUGHTEN RICHARD A
权利人:SCRIPPS CLINIC RES
摘要:A means for carrying out sequential, solid phase syntheses is disclosed as are methods of its use. The synthesis means comprises a foraminous container that encloses reactive particles. The particles are larger than any of the foraminae and have a known amount of covalently linked organic synthesis reactive functionality that is capable of reacting during the organic syntheses. The container and particles are substantially insoluble in water.

专利号:US-2005261474-A1
优先权日:2004-05-20
标题:Method of support-based chemical synthesis
发明人：HOUGHTEN RICHARD A; YU YONGPING
权利人:MIXTURE SCIENCES INC
摘要:A method of synthesis on a solid phase support is disclosed that provides a cleaved product containing a protecting group that would have been cleaved by reaction with anhydrous HF wherein the support is volatilized during cleavage of the protected product from the support by reaction with diluted HF.

专利号:US-12122769-B2
优先权日:2017-10-19
标题 :Synthesis of antibacterial aminoglycoside analogs
发明人：TREND RAISSA; DAPPEN MICHAEL; HENRY CHRISTOPHER E; GOLDBLUM ADAM AARON; AGGEN JAMES BRADLEY; MENDONÇA RICARDO FILIPE DE JESUS GONÇALVES; SARDINHA JOÃO CARLOS FALCÃO
权利人:CIPLA USA INC
摘要:The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.

专利号:AU-2022253019-A1
优先权日:2021-04-09
标题:Synthesis of rapamycin analog compounds