CAS: 1456632-40-8; 4-(N-(4-Cyclohexylbenzyl)-2-((2,3,4,5,6-Pentafluoro-N-Methylphenyl)Sulfonamido)Acetamido)Benzoic Acid
- 英文名称4-(N-(4-Cyclohexylbenzyl)-2-((2,3,4,5,6-Pentafluoro-N-Methylphenyl)Sulfonamido)Acetamido)Benzoic Acid
- 中文名称4-[[(4-环己基苯基)甲基][2-[甲基[(2,3,4,5,6-五氟苯基)磺酰基]氨基]乙酰基]氨基]苯甲酸
- IUPAC名称4-(N-(4-cyclohexylbenzyl)-2-((2,3,4,5,6-pentafluoro-N-methylphenyl)sulfonamido)acetamido)benzoic acid
- 其它别名4-[[(4-Cyclohexylphenyl)Methyl][2-[methyl[(2,3,4,5,6-Pentafluorophenyl)Sulfonyl]Amino]Acetyl]Amino]-Benzoic Acid Sh-4-54; Sh-4-54; 4-[[(4-Cyclohexylphenyl)Methyl][2-[methyl[(2,3,4,5,6-Pentafluorophenyl)Sulfonyl]Amino]Acetyl]Amino]-Benzoic Acid; Benzoic Acid, 4-[[(4-Cyclohexylphenyl)Methyl][2-[methyl[(2,3,4,5,6-Pentafluorophenyl)Sulfonyl]Amino]Acetyl]Amino]-; Sh-4-54 Usp/ep/bp; Sh-4-54, 10 Mm In Dmso
- CAS编号1456632-40-8
- MFCD编号:MFCD28143917
- 分子式:C29H27F5N2O5S分子量:610.6
- 产品CID: 691242
- 产品分类JAK/STAT Signaling → STAT
物理性质
MSDS等安全信息
上下游产品
benzyl 4-aminobenzoate pentafluorobenzenesulonyl chloride 4-amino-benzoic acid合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905110000-甲醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, Gunning PT. Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. ACS Med Chem Lett. 2013 Sep 8;4(11):1102-7. doi: 10.1021/ml4003138.
2: Arpin CC, Mac S, Jiang Y, Cheng H, Grimard M, Page BD, Kamocka MM, Haftchenary S, Su H, Ball DP, Rosa DA, Lai PS, Gómez-Biagi RF, Ali AM, Rana R, Hanenberg H, Kerman K, McElyea KC, Sandusky GE, Gunning PT, Fishel ML. Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics. Mol Cancer Ther. 2016 May;15(5):794-805. doi: 10.1158/1535-7163.MCT-15-0003. Epub 2016 Feb 12.
3: Linher-Melville K, Nashed MG, Ungard RG, Haftchenary S, Rosa DA, Gunning PT, Singh G. Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity. PLoS One. 2016 Aug 11;11(8):e0161202. doi: 10.1371/journal.pone.0161202.
合成参考文献
合成方法参考DOI号:10.1021/ml4003138
📝 需求与反馈
尽可能描述清楚需求与问题信息
