CAS: 126787-65-3; (2S,3R,4S,5R,6R)-2-((1H-Indol-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

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487-60-5 97753-82-7 1328-73-0

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D-galactose pentaacetate 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside O-acetyl-β-D-glucopyranoside)(1-acetyl-indol-3-yl)-(tetra-O-acetyl-β-D-glucopyranoside) indoxyl indigo 1-phenyl-1H-indol-3-yl-beta-D-galactopyranoside

📜(2R,3S,4S,5R,6S)-2-(Acetoxymethyl)-6-((1-Acetyl-1H-Indol-3-yl)Oxy)Tetrahydro-2H-Pyran-3,4,5-Triyltriacetate置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应 16.0H,以98%的收率获得3-吲哚基-Beta-D-吡喃半乳糖苷
参考文献:Improved Scalable Synthesis And Biological Activity Of "indoxyl-Gal," A Chromogenic Histochemical Used For The Identification Of Lac+ Organisms
标题:Improved Scalable Synthesis And Biological Activity Of "indoxyl-Gal," A Chromogenic Histochemical Used For The Identification Of Lac+ Organisms
摘要:披露了一种改进且操作简便的3-吲哚醇-β-D-半乳糖苷(吲哚醇-半乳糖)的合成方法.吲哚醇-半乳糖是一种敏感的着色组织化学试剂,用于识别β-半乳糖苷酶的酶活性(lacz基因).该合成方法的改进使得从可负担的起始材料中通过5个线性步骤获得25%的总产率,并且需要最少的色谱分离.生物测试确认使用膜过滤和改良的mi琼脂,对所有(100%,19株)大肠杆菌检测到了β-半乳糖苷酶活性.
Doi:10.2174/1570178615666180212152030