CAS: 104873-15-6; 1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6-[(1R)-1-Hydroxyethyl]-4-Methyl-3,7-Dioxo-, (4-Nitrophenyl)Methyl Ester, (4R,5R,6S)-
- 英文名称1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6-[(1R)-1-Hydroxyethyl]-4-Methyl-3,7-Dioxo-, (4-Nitrophenyl)Methyl Ester, (4R,5R,6S)-
- 中文名称4-硝基苄基(4R,5R,6S)-6-((R)-1-羟乙基)-4-甲基-3,7-二氧代-1-.[3.2.0]庚烷-2-羧酸甲酯
- IUPAC名称4-nitrobenzyl (4R,5R,6S)-6-((R)-1-hydroxyethyl)-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate
- 其它别名(4R,5R,6S)-4-Nitrobenzyl 6-((R)-1-Hydroxyethyl)-4-Methyl-3,7-Dioxo-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate; Meropenem - Cyclooxygenate; 4-Nitrobenzyl (4R,5R,6S)-6-[(1R)-1-Hydroxyethyl]-4-Methyl-3,7-Dioxo-1-Azabicyclo[3.2.0]-Heptane-2-Carboxylate; 1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6-[(1R)-1-Hydroxyethyl]-4-Methyl-3,7-Dioxo-, (4-Nitrophenyl)Methyl Ester, (4R,5R,6S)-
- CAS编号104873-15-6
- FDA UNII编号:827SJF9H85
- 分子式:C17H18N2O7分子量:362.34
- 产品CID: 87876
物理性质
MSDS等安全信息
上下游产品
(S)-2-{(2S,3S)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-propionic acid Acetic acid (2R,3R)-3-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-1-trimethylsilanyl-azetidin-2-yl ester (S)-2-{(2S,3S)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-thiopropionic acid S-phenyl ester (R)-2-{(2S,3S)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-propionic acid (4S,5R,6S)-3-(Diphenoxy-phosphoryloxy)-6-(1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester (4S,5S,6S)-6-(1-Hydroxy-ethyl)-4-methyl-3-((S)-1-{1-[(E)-4-nitro-benzyloxycarbonylimino]-ethyl}-pyrrolidin-3-ylsulfanyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 1-α-methyl RS-533 (4R,5R,6S)-3-(Diphenoxy-phosphoryloxy)-6-(1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905141000-异丁醇
2905142000-仲丁醇
2905399099-其他二元醇
2905499000-其他多元醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8093378-B2
优先权日:2006-04-28
标题 :Crystallization method for intermediates of carbapenem antibiotics
发明人：NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI
权利人:NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI; KANEKA CORP
摘要:An improved crystallization method for an azetidinone compound represented by the formula 1: , which is extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds. The present method provides crystals having higher quality and stability than conventional crystals and excellent filterability at the time of recovery; and an azetidinone compound having a low content of impurity, and which has a controlled particle size distribution of crystals and improved handleability and stability. The crystallization is carried out by adding a hydrocarbon solvent to a solution in which an azetidinone compound extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds is dissolved in the presence of a seed crystal in an amount of 200% by weight or less based on the weight of the azetidinone compound.
专利号:RU-2097383-C1
优先权日:1992-03-11
标题:Carbopenem derivatives and a method of their synthesis
