CAS: 97-77-8; Bis(Diethylthiocarbamoyl) Disulfide

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CAS号75-15-0 二硫化碳 | CAS号109-89-7 二乙胺 | CAS号147-84-2 二乙基二硫代氨基甲酸 | CAS号148-18-5 乙硫氮 | CAS号548761-51-9 2-(diethylcarba... | CAS号3699-30-7 N,N-二乙基二硫代氨基甲酸钾 | CAS号88245-23-2 bis(chlorothi°C... | CAS号3768-61-4 N-(diethylamino... | CAS号506-68-3 溴化氰 | CAS号105246-31-9 [(4-methylbenzo... | CAS号24486-01-9 Thiourea,N'-(4-... | CAS号95-30-7 二乙基二硫代氨基甲酸-2-苯并噻唑酯 | CAS号95-05-6 舒非仑 | CAS号88-10-8 N,N-二乙基氯甲酰胺 | CAS号88-11-9 二乙基硫代氨基甲酰氯 | CAS号13681-87-3 二乙基二硫代氨基甲酸铜(II) | CAS号14239-68-0 橡胶促进剂CED | CAS号13963-59-2 二乙基二硫代氨基甲酸铁盐 | CAS号14267-17-5 二乙基二硫代氨基甲酸镍

Sodium N,N-Diethyldithiocarbamate置于ammonium Cerium (Iv) Nitrate,氧气体系中,用 四氢呋喃 作为反应溶剂,化学反应 9.0H,以36%的收率获得产物二硫化四乙基秋兰姆
参考文献:Cerium Ammonium Nitrate-Catalyzed Aerobic Oxidative Coupling Of Dithiocarbamates: Facile Synthesis Of Thioureas And Bis(Aminothiocarbonyl)Disulfides
标题:Cerium Ammonium Nitrate-Catalyzed Aerobic Oxidative Coupling Of Dithiocarbamates: Facile Synthesis Of Thioureas And Bis(Aminothiocarbonyl)Disulfides
摘要:多种二取代和三取代硫脲通过二硫代氨基甲酸tea(或dabco)盐与胺在室温下使用硝酸铈铵(can)作为催化剂进行缩合反应,以高产率合成.这是一种一步法,无需分离异硫氰酸酯.该反应可能涉及胺对异硫氰酸酯的亲核加成,异硫氰酸酯是由二硫代氨基甲酸盐的氧化偶联以及随后双(氨基硫羰基)二硫化物的分解产生的.当使用二级胺和cs2作为反应物时,通过串联的亲核加成/氧化偶联反应,以中等至优异的产率获得了双(氨基硫羰基)二硫化物.在所有偶联反应中,氧化剂为空气,Can可能作为单电子转移催化剂发挥作用.
DOI:10.1039/c4Ra04628E

专利信息

专利号:US-2004152905-A1
优先权日:2003-01-31
标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-10253153-B2
优先权日:2015-04-24
标题 :Linker and support for solid phase synthesis of nucleic acid, and production method of nucleic acid using said support
发明人：MAETA ERI; MORI KENJIRO; HORIE SHOHEI; ITO TAKAHIKO; SAITO SHOICHIRO; NAGAO RYUHEI
权利人:NITTO DENKO CORP
摘要:The present invention provides a linker for solid phase synthesis of nucleic acid, which consists of a compound represented by the formula (I) or the formula (II), a support for solid phase synthesis of nucleic acid, which has a structure represented by the formula (III), and a production method of a nucleic acid, which uses the support: n nwherein each symbol is as defined in the SPECIFICATION.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人：NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.