CAS: 622-93-5; 3-(Diethylamino)Propan-1-Ol

该化合物是一种有机化合物,具有氢氧基和三级矿物质功能组别,这种双功能结构使它成为有机合成的多用途中间体,特别是用于生产药品,农用化学品和特殊化学品.它的第三组地雷能够用作催化剂或中和剂,而氢氧基组则允许进一步衍生.化合物在水和普通有机溶剂中表现出良好的溶解性,有利于将其纳入各种反应系统.其平衡的再活动性和稳定性使它适合于需要受控的甲胺-酒精相互作用的应用,例如聚合物的改变或表面活性合成.产品通常作为具有矿物质特征的清晰液体供应.

结构式图片

相似化合物

3161-51-1 2050-51-3 5515-83-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

ethyl 3-(diethylamino)propionate 1-benzoyloxy-3-diethylamino-propane n-butyl magnesium bromide diethylamine N,N-diethyl-N'-(6-methoxy-[8]quinolyl)-propanediyldiamineN,N-diethyl-N'-(6-methoxy-[8]quinolyl)-propanediyldiamine 5-benzyl-furan-2-carboxylic acid-(3-diethylamino-propyl ester) p-phenylenedi-acetic acid bis-(3-diethylamino-propyl ester)p-phenylenedi-acetic acid bis-(3-diethylamino-propyl ester) 5-fluoro-2-nitro-benzoic acid-(3-diethylamino-propylester); hydr°Chloride

合成工艺路线路线简述

    2,2-Diethylisoxazolidinium置于palladium On Activated Charcoal 氢气体系中,用 水 作为反应溶剂,化学反应生成 3-二乙氨基-1-丙醇
    参考文献:Ishidate,M. Et Al.,Chemical And Pharmaceutical Bulletin,1961,Vol. 9,P. 485-491
    标题:Ishidate,M. Et Al.,Chemical And Pharmaceutical Bulletin,1961,Vol. 9,P. 485-491

    海关参考信息

    专利信息


    专利号:US-7825244-B2
    优先权日:2005-06-10
    标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
    发明人:BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

    专利号:US-6538094-B2
    优先权日:1998-12-21
    标题:Process for synthesis of allophanate compounds and compositions including the product thereof
    发明人:TAZZIA CHARLES L
    权利人:BASF CORP
    摘要:The invention provides a process for preparing an allophanate-containing compound in the presence of a metal catalyst and a tertiary amine. In a preferred process, the tertiary amine compound also has a hydroxyl group. The hydroxyl group can react with the isocyanate functionality. Also disclosed is a process in which an allophanate-containing compound is prepared with copper acetate monohydrate as a catalyst. The allophanate-containing compound is used as a curing agent in coating compositions, particularly electrocoat coating compositions. The coating compositions are used to coat articles.

    专利号:US-3721650-A
    优先权日:1971-03-22
    标题 :Reactive hydroxyalkyl-onium catalysts for synthesis of polyoxazolidones
    发明人:D ALELIO G
    权利人:ALELIO G D
    摘要:A PROCESS FOR PREPARING POLYOXAZOLIDONES IS PROVIDED IN WHICH A POLYEPOXIDE IS REACTED WITH A POLYISOCYANATE IN THE PRESENCE OF CHEMICALLY REACTIVE HYDROXYALKYL-ONIUM CATALYSTS, SELECTED FROM THE CLASS OF AMMONIUM AND PHOSPHONIUM HALIDES HAVING AT LEAST TWO HYDROXYALKYL GROUPS. NOVEL POLYMERS ARE OBTAINED WHEN THESE NEW CATALYSTS CONTAINING TWO OR MORE HYDROXY GROUPS ARE CONDENSED WITH POLYISOCYANATES.

    专利号:US-7067554-B2
    优先权日:2000-05-30
    标 题 :Method for the synthesis of compounds of formula I and their uses thereof
    发明人:MJALLI ADNAN M M; GOPALASWAMY RAMESH; AVOR KWASI A; WYSONG CHRISTOPHER L; ANDREW PATRON
    权利人:TRANSTECH PHARMA INC
    摘要:This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of the interaction between the receptor for advanced glycated end products (RAGE) and its ligands, such as advanced glycated end products (AGEs), S100/calgranulin/EN-RAGE, β-amyloid and amphoterin, and for the management, treatment, control, or as an adjunct treatment for diseases in humans caused by RAGE. Such diseases or disease states include acute and chronic inflammation, the development of diabetic late complications such as increased vascular permeability, nephropathy, atherosclerosis, and retinopathy, the development of Alzheimer's disease, erectile dysfunction, and tumor invasion and metastasis.

    专利号:US-5637757-A
    优先权日:1995-04-11
    标 题 :One-pot synthesis of ring-brominated benzoate compounds
    发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
    权利人:GREAT LAKES CHEMICAL CORP
    摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

    专利号:US-2007021436-A1
    优先权日:2005-06-10
    标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Ida M.Bernhardsen, Et Al. Vapour-Liquid Equilibrium Study Of Tertiary Amines, Single And In Blend With 3-(Methylamino)Propylamine, For Post-Combustion Co2 Capture.
    [参考文献]: L M Leadbetter, Et Al. Neuromodulatory Role Of Serotonin In The Anticonvulsant Activity Of 2-Phenylbenzoate Of 3-Diethylamino-1-Propanol.Hcl (Jaw-669). Physiol Behav. 1989 Jul;46(1):35-7.
    [参考文献]: Agostino Pietrangelo, Et Al. Mechanistic Study Of The Stereoselective Polymerization Of D,L-Lactide Using Indium(Iii) Halides. J Am Chem Soc. 2010 Aug 25;132(33):11649-57.

    合成参考文献


    摘要:Pharmazie., 14(201), 1959 []
    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
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