CAS: 60091-87-4; 2-((4-Chloro-2-Nitrophenyl)Amino)Benzoic Acid

上下游产品

anthranilic acid 2,5-dichloronitrobenzene 2-chloro-5-bromonitrobenzene 2-fluoro-5-chloronitrobenzene N-(2-Amino-4-chlorophenyl)anthranilic acid N-(4-chloro-2-nitrophenyl)-N-{2-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amine clozaril

📜甲基硝基苯置于盐酸,Potassium Permanganate,Copper(L) Iodide,Palladium 10% On Activated Carbon,水,Potassium Carbonate,Potassium Iodide,Sodium Nitrite体系中,用 四氢呋喃,二氯甲烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 40.0H,反应生成 2-(4-氯-2-硝基苯基)氨基苯甲酸
参考文献:Design,Synthesis And Anticancer Activity Evaluation Of Diazepinomicin Derivatives
标题:Design,Synthesis And Anticancer Activity Evaluation Of Diazepinomicin Derivatives
摘要:合成了一系列地西泮米辛衍生物,并在体外评估了其对人类癌瘤细胞系的生长抑制活性.结果表明这种化合物具有抗癌选择性.根据结果,讨论了初步的结构-活性关系.
DOI:10.2174/1570180811310040011

专利信息

专利号:WO-2019239202-A1
优先权日:2018-06-11
标题:Novel & improved synthesis of antipsychotic drug
发明人：DUBEY DR RAJEEV KUMAR; SIRUGU BATTULA VENKAT RAO; POTLURI RAMESH BABU; POTLURI VAMSI KRISHNA; GARIKIPATI SHIVA KRISHNA
权利人:SMS PHARMACEUTICALS LTD
摘要:The present invention relates to novel as well as improved process for the preparation of Clozapine of Formula I which involves anti-narcotic and highly cost effective raw materials.