520-26-3 + 10236-47-2 = 520-33-2 + 480-41-1 + 90-74-4 反应条件:1.1 Catalysts: Glucosidase,β- Solvents: Dimethyl Sulfoxide,Water; 90 Min,Ph 5.5,95 °C 标题:Hydrolysis Of Flavanone Glycosides By β-Glucosidase From Pyrococcus Furiosus And Its Application To The Production Of Flavanone Aglycones From Citrus Extracts 作者:Shin,Kyung-Chul; Nam,Hyun-Koo; Oh,Deok-Kun 参考文献:Journal Of Agricultural And Food Chemistry 日期:2013 卷标:61(47) 页码:11532-11540
专利号:US-9149659-B2 优先权日:2012-11-14 标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER 权利人:COTY GERMANY GMBH 摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
专利号:US-11773128-B2 优先权日:2019-03-28 标题 :Electrocatalytic synthesis of dihydrochalcones 发明人:REDKO MIKHAIL; SAFFRON CHRISTOPHER M; JACKSON JAMES E 权利人:UNIV MICHIGAN STATE 摘要:The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant compound over a catalytic cathode in a reaction medium having a non-alkaline pH value, thereby forming a dihydrochalcone product; wherein the reactant compound has a structure according to Formula (I). The method can be used to prepare dihydrochalcone sweeteners, such as, for example, naringin dihydrochalcone and neohesperidin dihydrochalcone.
专利号:US-9700512-B1 优先权日:2016-05-10 标 题:Synthesis of hesperetin nanoparticles 发明人:Wagealla Mai Abdelrahman Elobeid; Al-Hassan Lulwah Saleh Mohammed; AWAD MANAL AHMED GASMELSEED; AL-GHAMDI NOUF ABDULLAH MUREET; VIRK PROMY; HENDI AWATIF AHMED 权利人:UNIV KING SAUD 摘要:A method of preparing hesperetin nanoparticles includes dissolving hesperetin in an organic solvent to form a solution; spraying the solution in boiling water while applying ultrasonic energy to form a mixture; and stirring the mixture for at least about 15 minutes at a speed of about 200-800 rpm to obtain the hesperetin nanoparticles.
专利号:US-2021161813-A1 优先权日:2018-08-10 标题:Comestible compositions for promoting atp synthesis 发明人:LEIGHTON HARRY J; CARTER KENNETH 权利人:MAINE NATURAL HEALTH COMPANY INC 摘要:Comestible compositions including a mitochondrial anti-oxidant, a fatty acid transport facilitator, and a substrate for ATP synthesis are disclosed. For example, a comestible composition may include D-ribose, acetyl-L-carnitine, and coenzyme Q10. Also disclosed are kits including the comestible compositions and methods of use of the comestible compositions.
专利号:FR-3002543-A1 优先权日:2013-02-28 标题:METHOD FOR THE ENZYMATIC SYNTHESIS OF FLAVONOIDS AND APPLICATION TO THE SYNTHESIS OF DIOSMETIN DERIVATIVES
专利号:US-6150403-A 优先权日:1997-10-14 标 题 :Topical compositions for regulating the oily/shiny appearance of skin 发明人:BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J 权利人:PROCTER & GAMBLE 摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.
1: Yang LJ, Xia S, Ma SX, Zhou SY, Zhao XQ, Wang SH, Li MY, Yang XD. Host-guest system of hesperetin and β-cyclodextrin or its derivatives: Preparation, characterization, inclusion mode, solubilization and stability. Mater Sci Eng C Mater Biol Appl. 2016 Feb 1;59:1016-24. doi: 10.1016/j.msec.2015.10.037. Epub 2015 Oct 23. doi: 10.1002/jmr.2509. Epub 2015 Sep 15. doi: 10.3892/mmr.2015.4625. Epub 2015 Nov 30. doi: 10.1016/j.jpba.2015.10.031. Epub 2015 Oct 27. doi: 10.1016/j.bmcl.2016.01.058. Epub 2016 Jan 22.
合成参考文献
参考文献:10.1186/1471-230x-11-81 摘要:Wu H, Jing Z, Tang X, Wang X, Zhang S, Yu Y, Wang Z, Cao H, Huang L, Yu Y, Wang Y. To compare the efficacy of two kinds of Zhizhu pills in the treatment of functional dyspepsia of spleen-deficiency and qi-stagnation syndrome: a randomized group sequential comparative trial. BMC Gastroenterol. 2011 Jul 15;11():81.