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芒柄花苷置于盐酸体系中,化学反应生成 刺芒柄花素
参考文献:Isoflavonoids In The Roots Of Thermopsis Fabacea D.C. (Leguminosae).
标题:Isoflavonoids In The Roots Of Thermopsis Fabacea D.C. (Leguminosae).
摘要:从thermopsis Fabacea D.C.(豆科植物)的根中分离出九种异黄酮(i-Ix).c. (豆科植物)中分离出了九种异黄酮类化合物(i-Ix).甲醇提取物可得到甲萘素(i)和大豆异黄酮(II),乙醚提取物可得到三叶异黄酮(iii),Dl-Maackiain(iv),染料木素(v)和 7,3'-二羟基-4'-甲氧基异黄酮(vi),乙酸乙酯提取物可得到甲萘素-7-O-β-D-葡萄糖苷(vii),大豆异黄酮(viii)和染料木素(ix).通过降解,光谱研究以及与真品直接比较,对这些化合物进行了鉴定.
DOI:10.1248/cpb.28.3686

专利信息

专利号:US-2012003164-A1
优先权日:1998-12-30
标题 :Cosmetic or dermatological composition containing an active agent which stimulates synthesis of the protein hsp 32 in the skin
发明人：NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC
权利人:NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC; DIOR CHRISTIAN PARFUMS
摘要:A dermatological or cosmetological composition for an external topical administration, included together with pharmaceutically and/or cosmetologically acceptable excipients: at least one UVA-stabilizing and/or UVB-stabilizing screening agent, at least one compound capable of activating the endogenous synthesis of Heat Shock Protein (HSP) 32 or a functional peptide fragment of such a protein, and forskolin or any extract containing it.

专利号:EP-1140000-B1
优先权日:1998-12-30
标 题 :Cosmetic or dermatological composition containing an active principle stimulating hsp 32 protein synthesis in the skin and cosmetic treatment method
发明人：NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC
权利人:DIOR CHRISTIAN PARFUMS
摘要:The invention concerns a dermatological or cosmetological composition, characterised in that it contains at least a compound capable of activating HSP 32 endogenetic synthesis or a functional peptide fragment of such a protein with pharmaceutically and/or cosmetologically acceptable carriers. The invention also concerns the use of a compound selected from the group consisting of procyanidolic oligomers (PCO) and their derivatives, caffeic acid esters and their derivatives and mixtures of said compounds, for preparing a composition designed to activate endogenetic synthesis of HSP 32 or a functional peptide fragment of such a protein.

专利号:US-2009062555-A1
优先权日:2007-08-28
标 题 :Synthesis of Isoflavone
发明人：HARMS ARTHUR E
权利人:HARMS ARTHUR E
摘要:The invention provides a process of manufacturing an isoflavone of the general formula 7 n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 each independently are H, OH, or an alkoxy, provided at least one of R 1 , R 2 , R 3 , and R 4 being OH, and one being alkoxy, or at least 2 groups being OH, comprising providing ketone (3) n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 are as stated above, combining (3) with trialkylortho formate, and a Lewis or Bronsted acid to produce the isoflavone, precipitating the isoflavone.

专利号:US-8263755-B2
优先权日:2006-11-20
标题:Synthesis of compounds useful as modulators of amyloid-beta production
发明人：FINDEIS MARK A
权利人:FINDEIS MARK A; SATORI PHARMACEUTICALS INC
摘要:As described herein, the present invention provides methods for preparing compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.

专利号:US-2014357576-A1
优先权日:2013-05-31
标题:Methods for enhancement of muscle protein synthesis
发明人：BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
权利人:NESTEC SA
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

专利号:WO-2015040533-A1
优先权日:2013-09-19
标题:Methods for enhancing muscle protein synthesis during energy deficit
发明人：BAILEY DAVID MARK; ZALTAS ERIC SCOTT; STELLINGWERFF TRENT; MOORE DANIEL RYAN; HAWLEY JOHN ALAN; BURKE LOUISE MARY
权利人:PREMIER NUTRITION CORP
摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis during periods of negative energy balance, or energy deficit. The methods include administering to an individual suffering from energy deficit a composition comprising protein in an amount from about 15 g to about 30 g during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof. The methods also include administering to an individual suffering from energy deficit a composition comprising protein during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof, wherein the protein is administered in a dose that is higher than doses typically recommended for individuals experiencing energy balance.