CAS: 424818-25-7; N-(Tert-Butyl)-3-Nitrobenzenesulfonamide

上下游产品

3-硝基苯磺酰氯 3-Nitrobenzenesulphonyl Chloride 121-51-7

📜硝基苯置于氯磺酸,氯化亚砜体系中,用 乙酸乙酯 作为反应溶剂,化学反应 22.0H,反应生成 N-叔丁基-3-硝基苯磺酰胺
参考文献: A Process For The Direct Synthesis Of Fedratinib Intermediate[fr] Procédé De Synthèse Directe D'Intermédiaire De Fedratinib
标题: A Process For The Direct Synthesis Of Fedratinib Intermediate[fr] Procédé De Synthèse Directe D'Intermédiaire De Fedratinib
摘要:本公开涉及一种直接合成fedratinib中间体的方法.特别地,本公开涉及一种直接合成3-氨基-N-(叔丁基)苯磺酰胺的方法.本公开方法具有多种优点,如操作条件方便,节省时间,易于纯化,操作成本低,产率和效率高,因此该方法在工业上是可行的.本公开方法使用的是无毒,廉价且易得的试剂,使得该方法具有成本效益,经济环保的特点.

专利信息

专利号:WO-2022269384-A1
优先权日:2021-06-24
标 题 :A process for the direct synthesis of fedratinib intermediate
发明人：DESAI ASIM HEMANTBHAI; PATIL SANJAY NIMBAJI; RADADIYA VAIBHAV GOVINDBHAI; DESAI JIGNASU THAKORBHAI; DUBEY RAJEEV RAMCHANDRA; CHOUBEY Ajit Kumar
权利人:AMI ORGANICS LTD
摘要:The present disclosure relates to a process for the direct synthesis of Fedratinib intermediate. Particularly, the present disclosure relates to a process for the direct synthesis of 3-amino-N- (tert-butyl)benzene sulfonamide. The process of the present disclosure has various advantages such as convenient operation conditions, time-saving process, easy purification, low operation costs, good yield and efficiency hence the process is industrially feasible. The use of non-toxic, inexpensive and easily available reagents, in the process of the present disclosure, makes the process cost-efficient economic and environmental friendly.

专利号:CN-114645068-A
优先权日:2020-12-21
标题 :A kind of enzyme-catalyzed synthesis method of aromatic amine compounds

专利号:CN-116947712-A
优先权日:2023-07-25
标题:Synthesis method of sulfonamide organic compound