CAS: 36255-44-4; 3-Bromo-1,1-Dimethoxypropane

相似化合物

14618-78-1 36865-41-5 102-52-3

上下游产品

CAS号6044-68-4 丙烯醛二甲缩醛 | CAS号67-56-1 甲醇 | CAS号107-02-8 丙烯醛 | CAS号149-73-5 原甲酸三甲酯 | CAS号65032-54-4 3-bromopropanal | CAS号59635-13-1 1,3-dibromo-1-m... | CAS号10035-10-6 氢溴酸 | CAS号102402-80-2 1-TRIMETHYLSTAN... | CAS号6044-68-4 丙烯醛二甲缩醛 | CAS号14315-97-0 1,1,3-三甲氧基丙烷 | CAS号31007-28-0 B-PIPERIDINOPRO... | CAS号14618-78-1 4,4-二甲氧基丁腈 | CAS号19060-15-2 4-氨基丁醛二甲缩醛 | CAS号114567-13-4 diethyl 2-(3,3-... | CAS号65032-54-4 3-bromopropanal | CAS号72931-54-5 (3,3-二异丙氧基丙基)三苯基溴化膦 | CAS号75424-63-4 5-oxo-5-phenylp...

丙烯醛二甲缩醛置于三甲基氯硅烷,4 A Molecular Sieve,Sodium Bromide体系中,用 乙腈 用作溶剂,化学反应 1.5H,以63%的收率获得1-溴-3,3-二甲氧基丙烷
参考文献:Feringa,Ben L.,Synthetic Communications,1985,Vol. 15,# 2,P. 87-90
标题:Feringa,Ben L.,Synthetic Communications,1985,Vol. 15,# 2,P. 87-90

专利信息

专利号:US-12378246-B2
优先权日:2019-04-11
标 题:Synthetic options towards the manufacture of (6R,10S)-10-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl} - 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-one
发明人：CUNIERE NICOLAS; FAN YU; KOLOTUCHIN SERGEI; MUKHERJEE SUBHA; SIMMONS ERIC M; SINGH AMARJIT; WEI CAROLYN S; XIAO YI; YUAN CHANGXIA; ZHENG BIN; WAGSCHAL SIMON ALBERT; BROGGINI DIEGO FERNANDO DOMENICO; CAO DUY CHI TRUNG; CHERNICHENKO KOSTIANTYN; LEMAIRE SEBASTIEN FRANCOIS EMMANUEL; BEN HAÃ?M CYRIL
权利人:BRISTOL MYERS SQUIBB CO; JANSSEN PHARMACEUTICA NV
摘要:Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.

专利号:US-4578475-A
优先权日:1983-02-11
标题 :Novel D-homosteroids
发明人：FUERST ANDOR; MUELLER MARCEL; KERB ULRICH; WIECHERT RUDOLF
权利人:HOFFMANN LA ROCHE
摘要:The novel D-homosteroids of the formula ##STR1## wherein R 1 represents a --CN, â•?NOH or â•?CH--NHOH group; R 2 represents oxo or, where R 1 represents a --CN group, R 2 represents oxo or a --OAc group; or R 1 and R 2 together with carbon atoms 2 and 3 of the steroid skeleton represents a [2,3-d]-fused isoxazole ring, a [3,2-c]-fused pyrazole ring, a [3,2-c]-fused N-acylated pyrazole ring or a [2,3-c]-fused furazan ring; Ac represents an acyl group; R 3 and R 4 represent methyl and R 5 and R 6 together represent an additional bond between carbon atoms 5 and 6 of the steroid skeleton; or R 4 and R 5 together represent --O--, R 3 represents hydrogen or methyl, and R 6 represents hydrogen; R 7 represents hydrogen, lower-alkyl or ethynyl; R 8 represents hydroxy or acyloxy; or R 7 and R 8 together represent a spiroether group of the formula ##STR2## or a spirolactone group of the formula ##STR3## the dotted 16,17-bond is an optional additional carbon-carbon bond; and the dotted 2,3-bond is an additional carbon-carbon bond when R 1 and R 2 together with carbon atoms 2 and 3 form the isoxazole or pyrazole ring or when R 2 represents a --OAc group, n inhibit the synthesis of progesterone in organisms and can be used for fertility control. The novel D-homosteroids can be manufactured by molecular modifications of other D-homosteoids.

专利号:WO-2024000877-A1
优先权日:2022-07-01
标题 :Preparation method for nicotine
发明人：WANG CHENG; LI JIANG; HE ZE
权利人:HUBEI HENO BIOLOGICAL ENG CO LTO
摘要:The present invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method for nicotine. The preparation method for nicotine comprises the following steps: photocatalytically synthesizing an intermediate N-tert-butyloxycarbonyl-nornicotine with 3-bromopyridine and N-tert-butyloxycarbonyl-proline as raw materials; then carrying out a reaction on the N-tert-butyloxycarbonyl-nornicotine and trifluoroacetic acid to remove the tert-butyloxycarbonyl group, so as to synthesize nornicotine; and finally, subjecting the nornicotine to a methylation reaction to synthesize nicotine. The preparation method for nicotine in the present invention has a short synthesis route, simple operations, high yield and low cost, and is suitable for industrial mass production.