CAS: 25878-23-3; D-Iditol

化学文摘社编号25878-23-3,是一种白色晶状固体,在水中可溶解,具有甜味,在各种食品产品中成为流行的糖替代品.D-Iditol被归类为多元醇,这意味着它含有多种羟基(-OH)组,有助于其湿性以及保持水分的能力.该化合物通常在制药工业中作为前身和配方用于其表面的二尿性特性.此外,D-Iditol还被用于生产某些种类的聚合物,并用作蛋白和酶的稳定剂,其低卡路里含量和对血糖含量影响最小,因此适合糖尿病饮食.然而,过量消费可能导致胃肠道不适,因为其消毒效应.

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CAS号57-48-7 果糖 | CAS号87-79-6 L-山梨糖

合成工艺路线路线简述

    📜L-(-)-艾杜糖置于sodium Amalgam体系中,化学反应生成D-艾杜糖醇
    参考文献:Fischer,E.; Fay,Chemische Berichte,1895,Vol. 28,P. 1982
    标题:Fischer,E.; Fay,Chemische Berichte,1895,Vol. 28,P. 1982

    海关参考信息

    专利信息


    专利号:US-10751419-B2
    优先权日:2014-05-01
    标题:Method for synthesis of reactive conjugate clusters
    发明人:MIGAWA MICHAEL T; YU JINGHUA; WAN W BRAD; PATEL SAYTEN P; VASQUEZ GUILLERMO; KINBERGER GARTH A; PRAKASH THAZHA P; SETH PUNIT P; SWAYZE ERIC E
    权利人:IONIS PHARMACEUTICALS INC
    摘要:Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are provided that enhance the synthesis of reactive conjugate clusters by reducing the number of synthetic steps required. The reactive conjugate clusters prepared using the improved methods don't include any transacylation impurities that are formed using existing methods. The improved methods also provide an increase in overall yield and a cost benefit over existing methods.

    专利号:US-9433605-B2
    优先权日:2006-03-23
    标 题 :Method for promoting synthesis of tissue collagen
    发明人:KAMIYA TOSHIKAZU; KAMIMURA AYAKO; KAWADA YOKO
    权利人:KYOWA HAKKO BIO CO LTD
    摘要:An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.

    专利号:US-10768157-B2
    优先权日:2015-10-20
    标 题:Materials and methods for the detection of trace amounts of substances in biological and environmental samples
    发明人:KABIR ABUZAR; FURTON KENNETH G
    权利人:KABIR ABUZAR; FURTON KENNETH G; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
    摘要:The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.

    专利号:WO-0134589-A1
    优先权日:1999-11-05
    标 题 :Semi-synthesis of baccatin iii from 9-dihydro-13-acetylbaccatin iii
    发明人:ZAMIR LOLITA
    权利人:ZAMIR LOLITA
    摘要:The present invention relates to a semi-synthetic process to convert a naturally occurring taxane into a suitable starting material for the synthesis of paclitaxel and related compounds. Specifically, the present invention relates to a process for the conversion of 9-dihydro-13-acetylbaccatin III into baccatin III which can then be used as starting material for the synthesis of taxane derivatives such as paclitaxel, docetaxel, cephalomannine and other taxanes structurally related to baccatin III.

    专利号:WO-2009128087-A3
    优先权日:2008-04-17
    标题:A method for synthesis of dibenzylidene sorbitol in high yields
    发明人:GUPTA VIRENDRAKUMAR; SINGH SAURABH; MAKWANA UMESH
    权利人:RELIANCE IND LTD; GUPTA VIRENDRAKUMAR; SINGH SAURABH; MAKWANA UMESH
    摘要:The invention relates to a method for synthesis of dibenzylidene sorbitol, in high yields, the method comprising heating dimethyl benzaldehyde and D-sorbitol in the presence of a bronsted acid catalyst at a temperature in the range of 50 to 150 degrees wherein the heating is carried out by microwave irradiation. The invention also relates to dibenzyidene sorbitol synthesized by the method and to Clarified polyolefin prepared by using dibenzyidene sorbitol.

    专利号:WO-9900440-A1
    优先权日:1997-06-26
    标 题:Synthesis of a dendritic polyalcohol
    发明人:IHRE HENRIK; HULT ANDERS
    权利人:PERSTORP AB; IHRE HENRIK; HULT ANDERS
    摘要:A process for a double stage convergent synthesis of a polymeric polyalcohol substantially and preferably built up from polyester units and composed of a monomeric or polymeric core to which at least one hyperbranched dendritic branch (dendron) consisting of a number of branching generations is added. The branching generations comprise a polymeric or monomeric branching chain extender having three reactive functions of which two are hydroxyl groups and one is a carboxyl group. The two hydroxyl groups of the branching chain extender is in a first step ketal protected by reacting said two hydroxyl groups with a ketal. A second step includes protection of the carboxyl group of said branching chain extender. The ketal protected branching chain extender and the carboxyl protected chain extender are then employed for repeated addition in a number of step yielding a predetermined number of branching generations. The thus synthesized dendron is finally added to a core having reactive hydroxyl or epoxide groups and the ketal protected hydroxyl groups are optionally deprotected.

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    主要参考文献

    参考标题:Synthesis Of R-Glucosides, Sugar Alcohols, Reduced Sugar Alcohols, And Furan Derivatives Of Reduced Sugar Alcohols
    摘要:Disclosed Herein Are Methods For Synthesizing 1,2,5,6-Hexanetetrol (Hto), 1,6 Hexanediol (Hdo) And Other Reduced Polyols From C5 And C6 Sugar Alcohols Or R Glycosides. The Methods Include Contacting The Sugar Alcohol Or R-Glycoside With A Copper Catalyst, Most Desirably A Raney Copper Catalyst With Hydrogen For A Time, Temperature And Pressure Sufficient To Form Reduced Polyols Having 2 To 3 Fewer Hydoxy Groups Than The Starting Material. When The Starting Compound Is A C6 Sugar Alcohol Such As Sorbitol Or R-Glycoside Of A C6 Sugar Such As Methyl Glucoside, The Predominant Product Is Hto. The Same Catalyst Can Be Used To Further Reduce The Hto To Hdo.

    合成参考文献


    参考文献:10.1093/pcp/pcq016
    摘要:Sasaki T, Mori IC, Furuichi T, Munemasa S, Toyooka K, Matsuoka K, Murata Y, Yamamoto Y. Closing plant stomata requires a homolog of an aluminum-activated malate transporter. Plant Cell Physiol. 2010 Mar;51(3):354–65.
    参考文献:10.1074/mcp.m900327-mcp200
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    参考文献:10.3233/jad-2010-1304
    摘要:Fernandez LL, Carmona M, Portero-Otin M, Naudi A, Pamplona R, Schröder N, Ferrer I. Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice. J Alzheimers Dis. 2010;19(3):1069–80. doi: 10.3233/jad-2010-1304.
    参考文献:10.1016/j.devcel.2009.12.018
    摘要:Kitamura E, Tanaka K, Komoto S, Kitamura Y, Antony C, Tanaka TU. Kinetochores Generate Microtubules with Distal Plus Ends: Their Roles and Limited Lifetime in Mitosis. Developmental Cell. 2010 Feb;18(2):248–59. doi: 10.1016/j.devcel.2009.12.018.
    参考文献:10.3390/md9061056
    摘要:Lordan S, Ross RP, Stanton C. Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases. Mar Drugs. 2011;9(6):1056–100.
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