CAS: 22712-78-3; 1,2-Dibromoethane-1,2-14C
- 相似结构搜索
- InChIKey: PAAZPARNPHGIKF-XPULMUKRSA-N
- 1S/C2H4Br2/c3-1-2-4/h1-2H2/i1+2,2+2
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
合成工艺路线路线简述
📜[1,2-14C]Ethene,溴 反应生成1,2-二溴乙烷-1,2-14C
参考文献:Bubner,M.;Guethert,I.,Zentralinst. Kernforsch. Rossendorf Dresden /ber./,1984,N 538: Jahresbe+
标题:Bubner,M.;Guethert,I.,Zentralinst. Kernforsch. Rossendorf Dresden /ber./,1984,N 538: Jahresbe+
海关参考信息
- 2903310000-1,2-二溴乙烷
2903399020-溴甲烷 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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主要参考文献
参考标题:Synthesis, In Vitro Covalent Binding Evaluation, And Metabolism Of 14C-Labeled Inhibitors Of 11β-Hsd1作者:Daqing Sun,Qiuping Ye,Xuelei Yan,Yosup Rew,Peter Fan,Xiao He,Min Jiang,Dustin L. Mcminn,Mario Monshouwer,Hua Tu,Jay P. Powers |发布日期:2014.11.13
摘要:In This Letter, We Reported The Design And Synthesis Of Three Potent, Selective, And Orally Bioavailable 11β-Hsd1 Inhibitors Labeled With 14C: Amg 456 (1), Am-6949 (2), And Am-7715 (3). We Evaluated The Covalent Protein Binding Of The Labeled Inhibitors In Human Liver Microsomes In Vitro And Assessed Their Potential Bioactivation Risk In Humans. We Then Studied The In Vitro Mechanism Of 2 In Human
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