CAS: 22445-41-6; 1-Iodo-3,5-Dimethylbenzene

上下游产品

CAS号172975-69-8 3,5-二甲基苯硼酸 | CAS号556-96-7 5-溴间二甲苯 | CAS号108-69-0 3,5-二甲基苯胺 | CAS号325142-93-6 2-(3,5-二甲基苯基)-4... | CAS号108-38-3 间二甲苯 | CAS号4102-48-1 2,5-二碘-1,3-二甲苯 | CAS号108-95-2 苯酚 | CAS号4102-53-8 4-碘-2,6-二甲基苯胺 | CAS号87-62-7 2,6-二甲基苯胺 | CAS号329685-40-7 3-苯基-1-丙基硼酸频哪酯 | CAS号325142-93-6 2-(3,5-二甲基苯基)-4... | CAS号556-96-7 5-溴间二甲苯 | CAS号5379-16-8 3,5-二甲基苯乙酮 | CAS号38360-81-5 3,5-二甲基苯硫酚 | CAS号4706-90-5 5-异丙基间二甲苯 | CAS号42288-46-0 3,5-二甲基苯乙酸 | CAS号461-97-2 5-氟间二甲苯 | CAS号92-53-5 4-苯基吗啉 | CAS号499-06-9 3,5-二甲基苯甲酸

间二甲苯置于喹喔啉,Palladium(II) Trifluoroacetate,2-硝基碘苯,N-乙酰甘氨酸,Silver(L) Oxide体系中,用69 %的收率获得1,3-二甲基-5-碘苯
参考文献:芳烃的空间控制等渗晚期 C-H 碘化
标题:芳烃的空间控制等渗晚期 C-H 碘化
摘要:芳基碘化物是有机化学中的关键基序,因为它们在金属介导的交叉偶联反应中作为关键的多功能性,用于合成和药物发现.这些支架通常由预功能化起始材料间接制备或通过亲电芳香族碘化协议.这些方法因其固有的选择性和/或所需起始材料的可用性而限于特定的区域异构体.在此,我们描述了通过基于双配体的双配体催化剂实现的等距 C-H/c-I 键复分解方法对芳烃进行空间控制的碘化,以实现芳烃限制的非定向 C-H 活化.该协议允许直接访问与传统方法相关的互补产品谱.它的合成效用通过广泛的范围和后期修饰的适用性得到证明.
Doi:10.1039/d3Sc00801K

专利信息

专利号:US-2015336866-A1
优先权日:2013-01-01
标题:Synthesis of difluoromethyl ethers and sulfides
发明人：HARTWIG JOHN; FIER PATRICK
权利人:UNIV CALIFORNIA
摘要:The synthesis of difluoromethyl ethers and sulfides with a simple, non-ozone-depleting reagent is described. The difluoromethylation of phenols with this reagent occurs at room temperature within minutes with exceptional functional group tolerance. The mild conditions makes possible tandem processes for the conversion of aryl boronic acids, aryl halides and arenes to difluoromethyl ethers. Mechanistic studies support a reaction pathway involving nucleophilic attack of the phenolate to difluorocarbene.

专利号:US-10487099-B2
优先权日:2017-06-30
标 题:Synthesis of hypervalent iodine reagents with dioxygen
发明人：POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN
权利人:TEXAS A & M UNIV SYS
摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.

专利号:US-2010063301-A1
优先权日:2006-03-15
标题 :Synthesis of thrombopoietin activity modulating compounds
发明人：PHILLIPS DEAN
权利人:LIGAND PHARM INC
摘要:Disclosed herein are various methods for synthesizing compounds that modulate thrombopoietin activity. Also disclosed are intermediates useful for the preparation of these compounds.

专利号:US-8114993-B2
优先权日:2007-02-06
标题:Use of aryl chlorides in palladium-catalyzed C-H bond functionalization
发明人：DAUGULIS OLAFS; CHIONG HENDRICH
权利人:DAUGULIS OLAFS; CHIONG HENDRICH; UNIV HOUSTON SYSTEM
摘要:A one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using chloroarenes and palladium catalysts is disclosed. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores.

专利号:US-12098126-B2
优先权日:2021-08-23
标题:Methods of iron catalyzed C-H bond amination
发明人：CHE CHI-MING; YOU TINGJIE
权利人:VERSITECH LTD; LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:Described herein is an iron(II)-phthalocyanine catalyzed C—H bond amination of alkyl azides. The catalyst is effective to produce intramolecular amination of saturated C—H bonds in moderate to excellent yields and the methods are tolerant of a wide scope of substrates. The methods described are useful for the synthesis of natural products derivatives and for the late-stage functionalization of pharmaceuticals.

专利号:US-3843719-A
优先权日:1969-05-14
标 题 :Synthesis of esters
发明人：BRADY D
权利人:PHILLIPS PETROLEUM CO
摘要:Preparation of esters of carboxylic acids in improved yields in shorter reaction times by use as catalysts organic compounds and complexes of certain Group VA and VIA elements. The method optionally uses a soluble iodide for further increase in yield.