CAS: 144429-71-0; Goniodiol 8-Acetate
- 英文名称Goniodiol 8-Acetate
- 中文名称8-乙酸哥纳香二醇酯
- IUPAC名称(1R,2S)-2-hydroxy-2-((R)-6-oxo-3,6-dihydro-2H-pyran-2-yl)-1-phenylethyl acetate
- 其它别名Goniodiol 8-Acetate; 2H-Pyran-2-One, 6-[2-(Acetyloxy)-1-Hydroxy-2-Phenylethyl]-5,6-Dihydro-, [6R*(1S*,2R*)]- (9Ci)
- CAS编号144429-71-0
- MFCD编号:MFCD23103611
- 分子式:C15H16O5分子量:276.29
- 产品CID: 677764
- 产品分类天然产物 → 酚类
物理性质
上下游产品
acetic anhydride (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-5,6-dihydropyran-2-one (Z)-(5R,6S,7R)-7-Acetoxy-5,6-dihydroxy-7-phenyl-hept-2-enoic acid methyl ester (1R,2R)-1-phenyl-but-3-ene-1,2-diol7,8-di-O-acetyl-goniodiol合成工艺路线路线简述
📜(4R,5R)-2,2-Dimethyl-5-Phenyl-[1,3]Dioxolane-4-Carbaldehyde置于吡啶,Chromium(Vi) Oxide,盐酸,叔丁基过氧化氢,4-二甲氨基吡啶,Bis(Acetylacetonate)Oxovanadium,三乙酰氧基硼氢化钠,1,8-二氮杂双环[5.4.0]十一碳-7-烯,汞,三氟乙酸,锌体系中,用 四氢呋喃,乙醚,二氯甲烷,苯 用作溶剂,化学反应 14.25H,反应生成8-乙酸哥纳香二醇酯
参考文献:Total Synthesis Of The Natural Goniodiol-8-Monoacetate From Cinnamyl Alcohol
标题:Total Synthesis Of The Natural Goniodiol-8-Monoacetate From Cinnamyl Alcohol
摘要:首次实现了以肉桂醇为起始物,通过sharpless不对称环氧化反应,历经十二步合成甾醇单乙酸酯的全程合成,总收率为7%.
Doi:10.1039/c39950000743
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2905122000-异丙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Enantioselective Synthesis Of (+)-Goniodiol And Of Its Naturally Occurring Acetylated Analogs作者:Jean-Philippe Surivet,Jacques Goré,Jean-Michel Vatèle |发布日期:1996.11
摘要:A Novel Route To Enantioenriched (+)-Goniodiol And Its Natural Acetylated Derivatives, Potent Cytotoxic Compounds, Is Described. The Main Features Of This Synthesis Are Transfer Of The Asymmetric Information Of The Scalemic Allenic Alcohol 5 To The α- And β- Carbons Through Highly Diastereoselective Reactions And Introduction Of The α,β-Unsaturated Lactone Moiety By The Ghosez' Methodology.
合成参考文献
合成方法参考DOI号:10.1055/s-2002-32977
📝 需求与反馈
尽可能描述清楚需求与问题信息
