CAS: 142-78-9; N-(2-Hydroxyethyl)Dodecanamide

该化合物是来自酸酸的有机化合物,一种在椰子油和棕榈内核油中常见的脂肪酸,其特征为氨化功能组,该功能组由酸脂与单乙醇胺反应产生,通常以粘性液体或蜡状固体为特征,视温度而定,以表面活性特性著称,使其在各种应用中有用,包括个人护理产品,洗涤剂和乳化剂.劳里酸单乙胺在水和有机溶剂中表现出良好的溶液性,这增强了其在配方中的效用.此外,该化合物具有温和的皮肤调节特性,适合化妆用途.该化合物一般被认为毒性低,但像许多薄化剂一样,在直接接触皮肤或眼睛时可能会引起刺激.其生物降解性是另一个有利的特征,它与日益增长的化学品使用环境关切是一致的.

结构式图片

相似化合物

7596-88-5 142-58-5 111-58-0

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号143-07-7 月桂酸 | CAS号141-43-5 2-氨基乙醇 | CAS号106-33-2 月桂酸乙酯 | CAS号112-16-3 十二酰氯 | CAS号111-82-0 月桂酸甲酯 | CAS号56895-81-9 dodecanoic (met... | CAS号7596-88-5 N-月桂酰甘氨酸 | CAS号14246-55-0 N-肉豆蔻酰甘氨酸 | CAS号2441-41-0 棕榈酰甘氨酸 | CAS号6333-54-6 硬脂酰甘氨酸 | CAS号14246-53-8 辛酰甘氨酸 | CAS号10431-84-2 4,5-二氢-2-十一烷基恶唑

合成工艺路线路线简述

    📜月桂酸置于氯化亚砜,三乙胺体系中,用 二氯甲烷 用作溶剂,化学反应 1.25H,反应生成N-(2-羟乙基)十二烷基酰胺
    参考文献:Alkyl Sulfonyl Derivatized Pamam-G2Dendrimers As Nonviral Gene Delivery Vectors With Improved Transfection Efficiencies
    标题:Alkyl Sulfonyl Derivatized Pamam-G2Dendrimers As Nonviral Gene Delivery Vectors With Improved Transfection Efficiencies
    摘要:构建了基于两亲性树枝状大分子的基因递送载体,其外围带有烷基磺酰疏水尾,以低代数pamam-G2为核,通过其一级氨基组与乙烯基砜衍生物的氮-迈克尔型加成反应进行功能化,作为表面工程的有效工具.虽然未修饰的pamam-G2无法有效地转染真核细胞,但功能化的pamam-G2树枝状大分子能够在低n/p比下结合dna,保护dna免受dnase I的消化,并显示出高转染效率和低细胞毒性.带有c18烷基链的树枝状大分子在cho-K1细胞中的转染效率比lipofectamine™ 2000高出3.1倍.以功能化pamam-G2为基础的树枝状聚合物复合物也显示出在血清存在下保持其转染特性的能力,并能够转染不同的真核细胞系,如neuro-2A和raw 264.7.利用乙烯基砜化学,制备了这些载体的荧光pamam-G2衍生物,作为分子探针,通过非网格蛋白依赖的机制确定细胞摄取和内化.
    Doi:10.1039/c0Ob00355G

    海关参考信息

    专利信息


    专利号:US-7329767-B2
    优先权日:2003-10-03
    标 题:Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
    发明人:DEWIS MARK L; JOHN THUMPLASSERIL V; ECKERT MARKUS A; COLSTEE JAN HERMAN; DA COSTA NEIL C; PEI TAO
    权利人:INT FLAVORS & FRAGRANCES INC
    摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formulan n nwherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

    专利号:US-8007841-B2
    优先权日:2003-10-03
    标 题 :Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
    发明人:JOHN THUMPLASSERIL V; ECKERT MARKUS A; DEWIS MARK L; COLSTEE JAN HERMAN; DA COSTA NEIL C
    权利人:INT FLAVORS & FRAGRANCES INC
    摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formula —(CH 2 ) n —, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

    专利号:WO-9507256-A1
    优先权日:1993-09-09
    标 题 :N-alkoxy polyhydroxy fatty acid amides and synthesis thereof
    发明人:SCHEIBEL JEFFREY JOHN; CONNOR DANIEL STEDMAN; FU YI-CHANG
    权利人:PROCTER & GAMBLE
    摘要:N-alkoxy polyhydroxy fatty acid amides surfactants are prepared in a substantially solvent-free process by reacting a fatty acid ester with an N-alkoxy polyhydroxy amine in the presence of a base catalyst, especially sodium methoxide. Thus, the palm fatty acid amides of N-(3-methoxypropyl) glucamine and N-(2-methoxyethyl) glucamine are prepared. Methods for laundering fabrics and for cleaning hard surfaces, especially glass, are also disclosed. Surfactant mixtures comprising the N-alkoxy polyhydroxy fatty acid amides and N-alkyl polyhydroxy fatty acid amides are also disclosed.

    专利号:US-10450525-B2
    优先权日:2014-08-27
    标题:Process for alaknolamide synthesis
    发明人:SUEN YAT FAN; LIU JOANNE; SIMARD FRANCOIS; LEUNG YUEN TING ANITA
    权利人:CHEVRON ORONITE CO
    摘要:The present invention is directed to a process of making alkanolamides wherein the “agingâ€? time is reduced and the diethanol amide to ester ratio in the finished product is increased. Further provided is an additive composition comprising an alkanolamide which contains a reduced amount of DEA and BHEP.

    专利号:RU-1825782-C
    优先权日:1990-09-17
    标 题:Method of synthesis of higher aliphatic acid monoethanolamides

    专利号:US-7718816-B2
    优先权日:2003-12-26
    标 题:Carboxamide derivative, processes for producing the same, and detergent composition
    发明人:YAJIMA TOSHIO; KAWASHIMA AKIKO
    权利人:LION AKZO KK
    摘要:To provide: a carboxamide derivative having reduced content of amide ester; a method for producing thereof; and a detergent composition containing the carboxamide derivative and having excellent low-temperature stability. One method for producing a carboxamide derivative is to react carboxamide, produced with a manufacturing method of carboxamide including 0.02% by weight to 0.18% by weight of amide ester, with hydrogen peroxide, wherein the method includes a carboxamide synthesis process to synthesize carboxamide by reacting diamine with fatty acid ester at a molar rate of 1.20 to 1.60. Another method for producing a carboxamide derivative is to react the carboxamide with monohaloalkylcarboxylic acid or a salt thereof. A carboxamide derivative is produced by the method for producing a carboxamide derivative. A detergent composition includes the carboxamide derivative. The carboxamide derivative is preferably amidoamine oxide or amide betaine.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Schmidberger, J. W.; Hepworth, L. J.; Green, A. P.; Flitsch, S. L., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 336.
    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 34(Suppl.1):18-34, 2015
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