CAS: 141-76-4; 3-Iodopropionicacid

相似化合物

627-32-7 6414-69-3 2517-76-2

上下游产品

chloropropionic acid methyl magnesium iodide β-Propiolactone diethyl ether a]pyrimidin-2-one3,4-dihydro-pyrido[1,2-a]pyrimidin-2-one 3-(3-methoxyphenoxy)propionic acid ethyl 3-chloropropanoate tetrahydro-1,3-thiazin-2,4-dione

📜丙烯酸置于氢碘酸体系中,20.0 °C,340.01 Kpa 条件下,以99%的收率获得3-碘丙酸
参考文献:通过异位反应生成Hx 和 Dx 气体进行无溶剂氢卤化和氘卤化
标题:通过异位反应生成Hx 和 Dx 气体进行无溶剂氢卤化和氘卤化
摘要:通过使用两室反应器异位产生接近化学计量的氢气和卤化氘气体,对烯烃进行无溶剂加氢和氘代卤化.在对底物进行化学和区域选择性转化后,可以分离卤化物产物,无需任何后处理或纯化步骤,使其成为一种清洁,劳动力,废物和成本效益高的方法.
Doi:10.1002/ejoc.202300785

专利信息

专利号:US-9346851-B2
优先权日:2008-02-22
标 题 :Chemical modification of proteins
发明人：BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN
权利人:BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN; RP SCHERER TECHNOLOGIES LLC
摘要:The invention relates to methods for selectively converting a cysteine residue in a peptide or protein to the dehydroalanine (Dha) residue. The method also works on selenocysteine and substituted cysteine and selenocysteine residues, resulting in the Dha residue which may be converted to any natural or unnatural amino acid residue desired without the alteration of the remainder of the peptide or protein. The invention also allows ligation of a desired peptide at any point rather than at a point where there should be a naturally occurring cysteine, thereby allowing native chemical ligation to be used in the synthesis of peptides that do not contain cysteine. The methodology allows for the synthesis of very large peptides.

专利号:US-9080119-B2
优先权日:2011-11-10
标 题:Synthesis of high caloric fuels and chemicals including pentanol from coal, natural gas, and biomass
发明人：HENRI JOHN; ZYGMUNT JAN; BERGGREN MARK; ZUBRIN ROBERT
权利人:PIONEER ENERGY INC; Pioneer Energy
摘要:In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.

专利号:US-9611186-B2
优先权日:2011-11-10
标 题 :Synthesis of high caloric fuels and chemicals via ketene and diketene intermediates
发明人：HENRI JOHN; ZYGMUNT JAN; BERGGREN MARK; ZUBRIN ROBERT
权利人:PIONEER ENERGY INC; Pioneer Energy
摘要:In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2008051323-A1
优先权日:2004-08-21
标 题 :Chloroquine drug compositions and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. n The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.

专利号:US-2007060499-A1
优先权日:2005-09-15
标 题 :Chloroquine combination drugs and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.