CAS: 13593-03-8; Quinalphos

上下游产品

CAS号57381-25-6 sodium quinoxal... | CAS号2524-04-1 氯硫代磷酸二乙酯 | CAS号1196-57-2 喹唑酮

📜Sodium Quinoxalin-2-Olate,O,O-二乙基硫代磷酰氯置于4-二甲氨基吡啶,苄基三乙基氯化铵,Sodium Dodecyl Sulfate,Potassium Carbonate体系中,用 水 用作溶剂,化学反应 2.5H,以94.1%的收率获得喹硫磷
参考文献:O,O-二烷基硫代氯代磷酸酯在水溶剂中酰化杂环醇阴离子的研究
标题:O,O-二烷基硫代氯代磷酸酯在水溶剂中酰化杂环醇阴离子的研究
摘要:摘要 研究了一些杂环醇阴离子与 O,O-二烷基硫代磷酸氯酯的酰化反应.通过使用有效的相转移催化剂 (Ptc)(苄基三乙基氯化铵 [bteac]),酰化催化剂 (Ac)(4-二甲氨基吡啶)和表面活性剂(十二烷基硫酸钠),在 50 oc 的水中获得更高的收率和更少的副产物),在弱碱性(ph 9.5∼10)条件下.该反应也可用于合成其他高产率的杀虫剂.图形概要
Doi:10.1080/10426507.2012.702824

专利信息

专利号:EP-0853625-B1
优先权日:1995-08-29
标 题:Synthesis of hydroxysulfone and related compounds
发明人：MATHRE DAVID J; SOHAR PAUL; MOODY DAVID; BLACKER ANDREW J
权利人:MERCK & CO INC; SYNGENTA LTD
摘要:This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.

专利号:EP-1611083-B1
优先权日:2003-03-25
标 题:Synthesis of 2-chloromethyl-6-methylbenzoic acid esters
发明人：MAIER CLAUS-JUERGEN; METZENTHIN TOBIAS; GRAESER JOACHIM; BICKER RICHARD; MANERO JAVIER
权利人:SANOFI AVENTIS DEUTSCHLAND
摘要:The invention relates to a method for producing compounds of formula (I) wherein R represents H, optionally halogen-substituted alkyl, cycloalkyl or aryl, alkyl-aryl or heteroaryl, and at least one CH2 group can be replaced by O in alkyl and cycloalkyl. Said compounds of formula (I) are valuable intermediates in the synthesis of PPAR agonists.

专利号:EP-1735276-B1
优先权日:2004-04-02
标题:Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues
发明人：HANSEN ERIK TORNGAARD; SABROE THOMAS PETER; CALVERLEY MARTIN JOHN; PEDERSEN HENRIK; DEUSSEN HEINZ-JOSEF WILHELM
权利人:LEO PHARMA AS
摘要:The present invention relates to novel methods for the preparation of intermediates which are useful in the synthesis of cacipotriol. The present invention relates further to the use of intermediates produced with said methods for making calcipotriol or calcipotriol monohydrate.

专利号:EP-1501848-B1
优先权日:2002-05-08
标 题 :Synthesis of locked nucleic acid derivatives
发明人：SORENSEN MADS DETLEF; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as alpha-L-oxy-LNA, amino-LNA, alpha-L-amino-LNA, thio-LNA, alpha-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues. (Formula I)

专利号:EP-1853592-B1
优先权日:2005-01-14
标题:Synthesis of himbacine analogs
发明人：THIRUVENGADAM TIRUVETTIPURAM K; WANG TAO; LIAO JING; CHIU JOHN S; TSAI DAVID J S; LEE HONG-CHANG; WU WENXUE; FU XIAOYONG
权利人:SCHERING CORP
摘要:The present invention relates to an improved process for preparing imbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer. An example of a step in the synthesis of such a himbacine analog is as follows: Formula (I)

专利号:EP-0406124-B1
优先权日:1989-06-29
标 题:Chiral polymers for the synthesis of enantiomerically pure amino-acids
发明人：JACQUIER ROBERT; CALMES MONIQUE; DAUNIS JACQUES
权利人:RHODIA CHIMIE SA
摘要:The invention relates to chiral polymers and their use in asymmetric synthesis operations for deracemization and optical inversion, said polymers being characterized by the fact that they include a chiral pattern, a functionalization pattern, and an optional cross-linking pattern. Application: chiral organic synthesis.