CAS: 13050-47-0; 3-Methylbenzoic Hydrazide

相似化合物

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上下游产品

CAS号120-33-2 3-甲基苯甲酸乙酯 | CAS号99-36-5 3-甲基苯甲酸甲酯 | CAS号99-04-7 间甲基苯甲酸 | CAS号1711-06-4 间甲基苯甲酰氯 | CAS号36718-84-0 (4-nitrophenyl)... | CAS号106710-48-9 3-[2-(3-methylb... | CAS号105576-60-1 4-amino-3-(3-me... | CAS号24023-73-2 2-氯甲基-5-(3-甲基苯基... | CAS号99-36-5 3-甲基苯甲酸甲酯 | CAS号99-04-7 间甲基苯甲酸 | CAS号66147-19-1 5-(3-甲基苯基)-1,3,... | CAS号143667-42-9 (2S,5R,6R)-3,3-... | CAS号75218-27-8 5-(3-甲基苯基)-3-巯基... | CAS号85681-45-4 5-(3-Methoxyphe... | CAS号59646-36-5 3-methyl-N-(3-m...

📜3-甲基苯甲酸甲酯置于一水合肼体系中,化学反应 10.0H,反应生成间甲苯甲酸酰肼
参考文献:三种新的芳酰hydr配体的氧化钒(v)配合物的合成,晶体结构和类胰岛素活性.
标题:三种新的芳酰hydr配体的氧化钒(v)配合物的合成,晶体结构和类胰岛素活性.
摘要:通过c,H,N元素分析,单晶x射线衍射,Uv / Vis和ir光谱设计,合成和表征了三种新型的氧化钒(v)配合物.配合物1:[vol 1 X](h 2 L 1 =(e)-N'-(2-羟基亚苄基)-3-甲基苯并肼,Hx =乙基麦芽酚= 2-乙基-3-羟基-4-吡喃酮),配合物2 : [vol 2(ch 3 O)(ch 3 Oh)],(h 2 L 2 = C 16 H 16 N 2 O 4 =(e)-N'-(2-羟基苄叉)-3,5-二甲氧基苯甲酰肼,通道3Oh =甲醇),络合物3:[vol 3 X](h 2 L 3 =(e)-N'-(3-乙氧基-2-羟基亚苄基)-3,5-二甲氧基苯并肼).测试了三种复合物的胰岛素样活性.正常和链脲佐菌素(stz)糖尿病小鼠均在胃内给药两周.发现以10.0和5.0Mg V.kg-1的剂量的复合物可以显着降低stz糖尿病小鼠的血糖水平,并且治疗的正常小鼠
Doi:10.1016/j.Jinorgbio.2019.03.020

专利信息

专利号:US-9085550-B2
优先权日:2005-01-21
标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands
发明人：FORMAN BARRY; YU DONNA
权利人:FORMAN BARRY; YU DONNA; HOPE CITY
摘要:Estrogen-Related Receptor (ERR) modulating compounds and methods for synthesis of said compounds are described.

专利号:US-8981092-B2
优先权日:2008-09-19
标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity
发明人：MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO
权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

专利号:US-2006189825-A1
优先权日:2005-01-21
标题:Ligands for estrogen related receptors and methods for synthesis of said ligands

专利号:US-6291504-B1
优先权日:1999-10-20
标题:Acylsemicarbazides and their uses
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; VIDWANS ANUP P; YUE EDDY W
权利人:DU PONT PHARM CO
摘要:The present invention relates to the synthesis of a new lass of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-2013131340-A1
优先权日:2005-01-21
标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands

专利号:US-2009318693-A1
优先权日:2005-01-21
标题:Ligands for estrogen related receptors and methods for synthesis of said ligands