CAS: 123-15-9; Methyl Valeraldehyde

该化合物是一种脂性藻类,其特征为五碳链和与第二碳相连的一组甲基,该化合物的分子分子式为C6H12O,在链的一端有一个功能性甲酰胺组(CHO),该物质具有反应性和特性,在室温中是一种无色液体,以其令人愉快的果味芳香闻名,使其在调味和香味应用中有用.在第二个对映体中出现阳性中心,导致其被称为2-甲基乙基苯并表明一种种族混合物.该化合物在有机溶剂中溶解,在水中具有中溶性.其反应包括参与典型的甲酰胺反应,如氧化和凝聚.安全考虑包括易燃性和潜在刺激效应,需要在实验室和工业环境中进行适当的处理和储存.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

propan-1-ol 3-methyl-3-propyl-oxiranecarboxylic acid ethyl ester 2-methylpentan-1-ol 2-methyl-2-pentenal2-methyl-2-propyl-1,3-propanediol 2-Amino-2-methyl-hexansaeure 2-methylpentylamine 2-methylpentan-1-ol

合成工艺路线路线简述

  • 合成目标产物 Methyl Valeraldehyde 主要起始原料 Carbon Monoxide And Trans-2-Pentene
  • (文献来源)合成步骤主要原料 Carbon Monoxide 和 Trans-2-Pentene
1-甲氧基-2-甲基戊烷-2-醇置于磷酸体系中,化学反应 3.0H,以83%的收率获得2-甲基戊醛
参考文献:Duchene,Alain; Mouko-Mpegna,David; Quintard,Jean-Paul,Bulletin De La Societe Chimique De France,1985,# 5,P. 787-793
标题:Duchene,Alain; Mouko-Mpegna,David; Quintard,Jean-Paul,Bulletin De La Societe Chimique De France,1985,# 5,P. 787-793

海关参考信息

专利信息


专利号:US-5484949-A
优先权日:1993-01-29
标题:Method for the synthesis of α β-unsaturated ketones
发明人:TSUKASHIMA KEIICHI; NAKAJIMA MASASHI; FUJIMARU MASAYOSHI; SUZUKI KENJI
权利人:NIPPON SODA CO
摘要:The present invention relates to a method for the synthesis of alpha , beta -unsaturated ketones which comprises, in the method for the synthesis of alpha , beta -unsaturated ketones represented by general formula reacting aldehydes represented by general formula R1CHO (where R1 is as defined above) with alkali metal salt of acetoacetic acid represented by general formula sence as a catalyst of 3-azabicyclo[3,2,2]nonane, a cyclic secondary amine represented by general formula (1) (1) a cyclic secondary amine represented by general formula (2) (2) (where, l is 1 or more and up to 6, a ring with N is a 6-membered, 7-membered or 8-membered ring, the two neighbors of N are methylene, R3 is a lower alkyl group, its substitution position is at a carbon atom other than two those adjacent to N, and is an alicyclic group or a phenol group), or a secondary amine represented by general formula (3) CH3NHCH2R4(3) in a mixuture solvent of water and water-insoluble organic solvent, while keeping the pH constant with mineral acid, and by adjusting an amount of water.

专利号:US-6680395-B2
优先权日:2000-03-04
标 题:Method for the synthesis of straight-chain aliphatic carboxylic acids from aldehydes
发明人:SPRINGER HELMUT
权利人:CELANESE CHEM EUROPE GMBH
摘要:The invention relates to a non-catalysed method for the synthesis of straight-chain aliphatic carboxylic acids by oxidation of straight-chain aldehydes with oxygen-containing gas mixtures. The invention is characterised in that during the novel process of oxidation branched aldehydes are present in the reaction mixture.

专利号:US-2023212788-A1
优先权日:2020-03-26
标 题:New method for automated on-demand biomolecular array synthesis
发明人:ZHANG YIXIN; LIN WEILIN
权利人:UNIV DRESDEN TECH
摘要:The invention provides an amphiphilic coating for the direct and rapid synthesis of an array of peptides and small molecular compounds on a planar surface of a solid support, comprising a hydrophilic chemical structure and a lipophilic group, wherein said peptides and small molecular compounds differ from spot to spot from each other in the chemical structure, characterized in that said amphiphilic coating possesses low wettability to polar aprotic solvents used in the array synthesis; said amphiphilic coating possessing low wettability is designed that it can be converted to a coating possessing high wettability by hydrolysis of the lipophilic group; and said amphiphilic coating comprises an amino group for the reaction with an electrophilic reagent. The invention further provides a solid support comprising said amphiphilic coating and a method for method for the direct and rapid synthesis of an array of peptides and small molecular compounds on a planar surface of a solid support, wherein said planar surface of a solid support comprises said amphiphilic coating. Said method includes the enhancing of the wettability of a glass surface to organic solvents to realize automated on-demand biomolecular array synthesis comprising both, peptides and small molecular compounds. The amphiphilic surface can be switched to a hydrophilic surface, resulting in high density arrays suitable for protein- and cell-based screening.

专利号:WO-2024259491-A1
优先权日:2023-06-23
标 题:New synthesis method
发明人:FORD DANIEL; POZNAKS VIKTORS; FOTINS JURIS; ÄŒERÅ…AKS DMITRIJS
权利人:THE HEART RES INSTITUTE LTD
摘要:The present disclosure generally relates to a process for the synthesis of AZD6482. In particular, the present disclosure also relates to a process for the synthesis of enantiomerically pure AZD6482. The present disclosure also relates to a process for the synthesis of enantiomerically pure intermediates. The present disclosure also relates to compounds prepared by the processes and the use of such compounds to prepare compositions and to treat disorders.

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人:CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

专利号:US-9403841-B2
优先权日:2012-01-25
标题:Phragamalin limonoids for the treatment of sexual dysfunction
发明人:WIKBERG JARL; JIRGENSONS AIGARS; LIEPINSH EDVARDS
权利人:DICOTYLEDON AB
摘要:The present invention relates to novel chemical compounds, to methods for synthesis of such compounds, and to the use of these novel compounds in the synthesis of other chemical compounds that, inter alia, may be used in the treatment of sexual dysfunction, and for eliciting enhancing effects on sexual behavior. The invention also relates to remarkable biological properties of the novel compounds in their capacity of inducing aggressive behavior.
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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Total Synthesis Of (−)-Sarain A
作者:Michael H. Becker,Peter Chua,Robert Downham,Christopher J. Douglas,Neil K. Garg,Sheldon Hiebert,Stefan Jaroch,Richard T. Matsuoka,Joy A. Middleton,Fay W. Ng,Larry E. Overman |发布日期:2007.10.1
摘要:Studies Toward The Complex Marine Alkaloid Sarain A. Various Strategies Were Conceived, Setbacks Encountered, And Solutions Developed, Ultimately Leading To A Successful Enantioselective Total Synthesis. Our Route To (+)-Sarain A Features A Number Of Key Steps, Including An Asymmetric Michael Addition To Install The C4'-C3'-C7' Stereotriad, An Enoxysilane-N-Sulfonyliminium Ion Cyclization To Set The C3 Quaternary

合成参考文献


摘要:Mase, N., Science of Synthesis: Asymmetric Organocatalysis, (2012) 1, 176.
摘要:Jie, X.; Su, W., Science of Synthesis, (2022) , 11.
摘要:Xu, L.; Wu, X.; Xiao, J., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 297.
摘要:Wu, X.; Xiao, J., Science of Synthesis: Water in Organic Synthesis, (2012) 1, 268.
摘要:Inokuma, T.; Takemoto, Y., Science of Synthesis: Asymmetric Organocatalysis, (2012) 2, 445.
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