CAS: 120882-22-6; Desfuroyl Ceftiofur
该化合物是乙硫的一种关键的代谢物,是第三代甲状腺素抗生素抗生素,该化合物广泛用于兽医学,用于其针对克氏阳性和克氏阴性病原体的广谱抗菌性活动.由于纯度超过85%,它确保了研究和分析应用的可靠性能,如残留物研究和药用植物研究.它的高纯度使它适合用作HPLC和LC-MS方法的参考标准.Desfururoyl Ceftiofur对于监测药物代谢和确保食品生产动物的监管标准得到遵守特别有用.该化合物的稳定性和特性进一步增强了其在科学和诊断环境中的效用.
- 英文名称Desfuroyl Ceftiofur
- 中文名称去呋喃甲酰基头孢噻呋
- IUPAC名称(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 其它别名(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]°Ct-2-ene-2-carboxylic Aci; Desfuroyl Ceftiofur; (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]°Ct-2-ene-2-carboxylic Acid; 5-Thia-1-azabicyclo(4.2.0)°Ct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(mercaptomethyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-
- CAS编号120882-22-6
- MFCD编号:MFCD00877095
- 分子式:C14H15N5O5S3分子量:429.49
- 产品CID: 280156
- 产品分类原料药 → 抗生素类药物 → 头孢菌素类药
物理性质
合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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主要参考文献
1: Gaire TN, Salas J, Dunmire KM, Paulk CB, Tokach MD, Nagaraja TG, Volkova VV. Faecal concentrations of ceftiofur metabolites in finisher pigs administered intramuscularly with ceftiofur. Vet Med Sci. 2021 May 15. doi: 10.1002/vms3.520. Epub ahead of print. 66(4):859-864.
6:363. doi: 10.3389/fvets.2019.00363.
4: Zhang M, Yang F, Yu HJ, Kang TJ, Ding YH, Yu ML, Wang QK, Zhu YX, Yang F. Pharmacokinetics of ceftiofur sodium in cats following a single intravenous and subcutaneous injection. J Vet Pharmacol Ther. 2019 Nov;42(6):602-608. doi: 10.1111/jvp.12814. Epub 2019 Sep 17. 15(1):272. doi: 10.1186/s12917-019-2008-4.
合成参考文献
参考文献:10.1111/j.1365-2885.2011.01311.x
摘要:Credille BC, Giguère S, Berghaus LJ, Burton AJ, Sturgill TL, Grover GS, Donecker JM, Brown SA. Plasma and pulmonary disposition of ceftiofur and its metabolites after intramuscular administration of ceftiofur crystalline free acid in weanling foals. J Vet Pharmacol Ther. 2012 Jun;35(3):259–64. doi: 10.1111/j.1365-2885.2011.01311.x.
参考文献:10.1186/s12917-015-0578-3
摘要:Beyer A, Baumann S, Scherz G, Stahl J, von Bergen M, Friese A, Roesler U, Kietzmann M, Honscha W. Effects of ceftiofur treatment on the susceptibility of commensal porcine E.coli – comparison between treated and untreated animals housed in the same stable. BMC Veterinary Research. 2015 Oct 15;11(1):265. doi: 10.1186/s12917-015-0578-3.
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