CAS: 114389-70-7; (1S,2R)-2-(Dibutylamino)-1-Phenyl-1-Propanol

该化合物是一种具有特定立体化学特征的手性化合物,对其生物活动至关重要.该化合物具有苯乙醇杂念,表明存在附于氢氧化硫组的苯环,以及促成其矿质特征的二丁基氨基化合物组.二丁基氨基氨基化合物的存在表明,该化合物可能表现出严重的亲脂性,有可能影响其溶性及生物系统中的渗透性.(S)和(1R)称的立体化学学表明,该化合物可能与生物目标有选择地相互作用,例如感应器或酶,这可能导致不同的药理效应.

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CAS号542-69-8 碘代正丁烷 | CAS号37577-28-9 左旋去甲麻黄碱

合成工艺路线路线简述

    📜1-碘丁烷,左旋去甲麻黄碱置于potassium Carbonate体系中,用 乙醇 用作溶剂,以67%的收率获得(1S,2R)-2-(二丁氨基)-1-苯基-1-丙醇
    参考文献:用于将二乙基锌高度对映选择性加成到醛中的新型手性催化剂
    标题:用于将二乙基锌高度对映选择性加成到醛中的新型手性催化剂
    摘要:发现(+)-去氧麻黄碱的旋光氨基硫代乙酸酯衍生物可作为将二乙基锌对醛对映选择性加成的有效催化剂.该反应提供了ee>=99%的光学活性仲醇.
    Doi:10.1016/s0040-4039(96)02027-8

    海关参考信息

    专利信息


    专利号:US-2006111333-A1
    优先权日:2004-11-20
    标 题 :Structural, behavioral characterization, and synthesis of attractants for migratory lamprey

    专利号:US-7557097-B2
    优先权日:2004-11-20
    标题:Structural, behavioral characterization, and synthesis of attractants for migratory lamprey
    发明人:SORENSEN PETER W; HOYE THOMAS R; FINE JARED M; DVORNIKOVS VADIMS; WANG JIZHOU; VRIEZE LANCE A
    权利人:UNIV MINNESOTA
    摘要:Compounds that function as lamprey attractants and methods.

    专利号:US-6921487-B2
    优先权日:2002-08-14
    标题 :Removal of zinc salts from nonaqueous synthesis solutions comprising zinc alkoxides or zinc amides
    发明人:SORGER KLAS; PETERSEN HERMANN; STOHRER JUERGEN
    权利人:CONSORTIUM ELEKTROCHEM IND
    摘要:A process for removing zinc from organic solutions comprising zinc alkoxides or zinc amides, includes admixing the solution with an alkylating, arylating, acylating or silylating agent in the presence of a precipitating reagent having at least two nitrogen donors and subsequently removing the precipitated solid.

    专利号:DE-10237274-A1
    优先权日:2002-08-14
    标题:Process for the separation of zinc salts from zinc alcoholates or non-aqueous synthesis solutions containing zinc amides

    专利号:US-2004089613-A1
    优先权日:2002-08-14
    标 题:Removal of zinc salts from nonaqueous synthesis solutions comprising zinc alkoxides or zinc amides

    专利号:DE-10237274-B4
    优先权日:2002-08-14
    标题 :Process for the separation of zinc salts from zinc alcoholates or non-aqueous synthesis solutions containing zinc amides

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Goldfuss, B., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 420.
    摘要:Goldfuss, B., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 348.
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