CAS: 77-49-6; 2-Methyl-2-Nitro-1,3-Propanediol

相似化合物

115-69-5 126-11-4 594-70-7

上下游产品

CAS号50-00-0 甲醛 | CAS号79-24-3 硝基乙烷 | CAS号71481-64-6 methanol with f... | CAS号25245-58-3 2-甲基-1,2,3-丙三醇 | CAS号24395-58-2 2-(hydroxyamino... | CAS号6270-16-2 3-硝基-2-丁醇,异构体混合物 | CAS号76-39-1 2-甲基-2-硝基-1-丙醇 | CAS号10359-57-6 4-Methyl-4-nitr... | CAS号115-69-5 2-氨基-2-甲基-1,3-丙... | CAS号17144-55-7 1,3-Dioxane,2-(... | CAS号1194-36-1 1,3-Dioxane,5-m... | CAS号65102-43-4 N-(1,3-dihydrox... | CAS号875-09-2 3,5-dimethyl-5-...

聚合甲醛,硝基乙烷置于sodium Carbonate体系中,用 水 作为反应溶剂,化学反应 0.5H,以88.9%的收率获得产物2-硝基-2-甲基-1,3-丙二醇
参考文献:二(2-叠氮乙酸)-2'-甲基-2'-硝基-1',3'-丙 二酯及其制备方法
标题:二(2-叠氮乙酸)-2'-甲基-2'-硝基-1',3'-丙 二酯及其制备方法
摘要:本发明公开了一种二(2-叠氮乙酸)-2'-甲基-2'-硝基-1',3'-丙二酯,其结构式如(I)所示:本发明所涉及的化合物属于含能增塑剂,具有热稳定性较好,感度较低等特点,主要用于固体推进剂,发射药等领域.

专利信息

专利号:US-8304409-B2
优先权日:2002-07-03
标 题:Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
发明人：EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI
权利人:EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI; NICOX SA
摘要:The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one nitrosated NSAID, and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one nitrosated NSAID, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating inflammation, pain and fever; for treating gastrointestinal disorders; for facilitating wound healing; for treating and/or preventing gastrointestinal, renal and/or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds; for treating inflammatory disease states and/or disorders; and for treating and/or preventing ophthalmic diseases and/or disorders.

专利号:US-9670134-B2
优先权日:2013-03-28
标 题:Synthesis of (2-nitro)alkyl (meth)acrylates via transesterification of (meth)acrylate esters
发明人：SATHIOSATHAM MUHUNTHAN; WILCZYNSKI ROBERT
权利人:ANGUS CHEMICAL
摘要:Provided is a process for making (2-nitro)alkyl (meth)acrylate compounds of formula I: wherein n, R, R 1 , R 2 , R 3 , R 4 , R 6 , R 7 , and n are as defined herein, by a transesterification reaction between a nitroalcohol compound and a (meth)acrylate compound in the presence of a transesterification catalyst and a free radical inhibitor.

专利号:DE-112014001664-T5
优先权日:2013-03-28
标题:Synthesis of (2-nitro) alkyl (meth) acrylates by transesterification of (meth) acrylate esters

专利号:US-2016046558-A1
优先权日:2013-03-28
标题 :Synthesis of (2-nitro)alkyl (meth)acrylates via transesterification of (meth)acrylate esters

专利号:WO-2014158445-A1
优先权日:2013-03-28
标 题 :Synthesis of (2-nitro)alkyl (meth)acrylates via transesterification of (meth)acrylate esters