CAS: 5328-37-0; (2R,3S,4S)-2,3,4,5-Tetrahydroxypentanal

相似化合物

58-86-6 609-06-3 25990-60-7

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CAS号1365758-43-5 | CAS号1350446-55-7 3-O-β-D-galacto... | CAS号473-81-4 DL-甘油酸 | CAS号64-18-6 甲酸 | CAS号608-53-7 L-Arabinoic acid | CAS号497-09-6 L-(-)-甘油醛 | CAS号14227-90-8 三乙酰基-β-L-溴代阿拉伯糖 | CAS号513-86-0 3-羟基-2-丁酮 | CAS号513-85-9 2,3-丁二醇 | CAS号64-17-5 乙醇 | CAS号504-63-2 1,3-丙二醇

甲基-L-吡喃阿拉伯糖苷置于cuggh Metallopeptide Based Glycosidase,双氧水,Sodium Ascorbate体系中,用 甲醇,Aq. Phosphate Buffer,水 作为反应溶剂,化学反应 8.0H,反应生成 L-阿拉伯糖
参考文献:使用基于过氧化氢/金属肽的糖苷酶模拟物从头进行糖测序的碳水化合物水解的范围和局限性
标题:使用基于过氧化氢/金属肽的糖苷酶模拟物从头进行糖测序的碳水化合物水解的范围和局限性
摘要:酸性水解通常用作将寡糖和多糖分解为单糖单元进行结构分析的第一步.酸水解虽然易于设置并适合质谱检测,但并非没有缺点.例如,环破坏副反应和降解产物,以及优化从分析物到分析物的条件的困难,极大地限制了其广泛的用途.在这里,我们报告基于过氧化氢/ Cuggh金属肽的糖苷酶模拟物设计的研究,以更有效和可控制地水解碳水化合物.用人工糖苷酶用机器人液体处理系统以高通量形式筛选了由十种常见单糖底物以及寡糖底物组成的甲基糖苷文库,以分析其水解活性.
DOI:10.1016/j.Carres.2018.01.008

专利信息

专利号:US-2008293096-A1
优先权日:2004-04-30
标 题:Enzyme and Template-Controlled Synthesis of Silica from Non-Organic Silicon Compounds as Well as Aminosilanes and Silazanes and Use Thereof
发明人：MULLER WERNER E G; SCHRODER HEINZ C
权利人:MULLER WERNER E G; SCHRODER HEINZ C
摘要:The present invention relates to a method for synthesis of amorphous silicon dioxide (silica, condensation products of silicic acid) and other polymeric metal (IV) compounds from non-organic silicon compounds or metal (IV) compounds as well as from aminosilanes and silazanes, whereby (I) a template (collagen or another molecule, interacting with orthosilicic acid or polymeric silicic acid and salts thereof or other metal (IV) compounds) and (2) a silicase/carbonic anhydrase or a silicatein or similar polypeptide are used for synthesis. Said invention also relates to the technical use thereof.

专利号:US-6172205-B1
优先权日:1997-12-11
标题 :Synthetic process toward total synthesis of eleutherobin and its analogues and uses thereof
发明人：DANISHEFSKY SAMUEL J; CHEN XIAO-TAO; GUTTERIDGE CLARE E; BHATTACHARYA SAMIT K; ZHOU BISHAN
权利人:TRUSTEES OF COLUMBIA IN THE CI
摘要:This invention provides a process for the preparation of a Eleutherobin derivative of the formula: n wherein R 1 is a hydrogen, ester, nitrile or C 2 H 4 —R wherein R 4 is a carbohydrate, an alcohol an amine, an amide, an alkyne, or, R 2 is a linear or branched alkyl moiety, R 3 is an ester, an amide, a carbamate, an acetal compound,an ether or a urethane, R 4 is a hydrogen or CH 2 ,position C 2 and C 3 is cis or trans,position C 8 is α or β and a compound is produced having the structures: n Additionally, this experiment provides a method for inhibiting growth of cancerous cells comprising contracting an amount of Eleutherobin derivative effective to inhibit the growth of said cells. Further provided is a method for treating cancer in a subject which comprises administering to the subject a therapeutically effective amount of the Eleutherobin derivative.

专利号:US-5286877-A
优先权日:1993-02-01
标 题:Synthesis of 1,4-dideoxy-1,4-imino-L-arabinitol
发明人：BEHLING JAMES R; MEDICH JOHN R; BABIAK KEVIN A; FLEET GEORGE W J
权利人:SEARLE & CO
摘要:1,4-Dideoxy-1,4-imino-L-arabinitol is chemically synthesized from D-lyxonolactone by formation of the pyrrolidine ring by joining the nitrogen between C-1 and C-4 and inversion of configuration at both C-2 and C-4, with the C-3 and C-5 hydroxyl groups being protected throughout the synthesis sequence by benzylidenation. The product is preferably isolated as the hydrochloride salt and is useful as an inhibitor of α-glucosidase and human immunodeficiency virus (HIV).

专利号:US-2011165641-A1
优先权日:2006-03-31
标 题 :Synthesis of 1,2,4-Butanetriol Enantiomers from Carbohydrates
发明人：FROST JOHN W
权利人:UNIV MICHIGAN STATE
摘要:A bioengineered synthesis scheme for the production of L-1,2,4-butanetriol, D-1,2,4-butanetriol and racemic mixtures thereof from a carbon source is provided. Methods of producing L-1,2,4-butanetriol, D-1,2,4-butanetriol and racemic mixtures thereof are also provided. Methods are also provided for converting D-1,2,4-butanetriol and L-1,2,4,-butanetriol to D,L-1,2,4-butanetriol trinitrate.

专利号:WO-2025083208-A1
优先权日:2023-10-19
标题 :Synthesis of morpholine derivatives and compounds therefore
发明人：BUESCHLEB MARTIN; BEAUFILS FLORENT; PROUDFOOT JOHN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to a synthesis method for morpholine derivatives, including a ring-formation out of a 1,2-amino alcohol and a compound of formula (I) whereby LG is a nucleophilic leaving group and R1 to R7 are as herein defined.

专利号:US-10961539-B2
优先权日:2015-06-11
标题 :Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same
发明人：PARK SUNG-HOON; ZHOU SHENGFANG; ASHOK SOMASUNDAR; SEOL EUN HEE; AINALA SATISH KUMAR
权利人:NOROO IC CO LTD; NOROO R&C CO LTD
摘要:The present invention relates to a promoter system inducing expression of 3-hydroxypropionic acid (3-HP) and a method of biologically producing 3-HP using the same. To improve production of 3-HP in a biological manner, continuous synthesis of new enzymes having enzyme activity is necessary. As a result of screening 3-HP reactive transcription regulators and 3-HP reactive promoters from several microorganisms including Pseudomonas denitrificans , it was confirmed that the transcriptions regulations and promoters are composed of LysR proteins and particular gene nucleotide sequences binding to the LysR proteins. Therefore, the 3-HP inducible system is expected to be effectively used to regulate 3-HP metabolic pathways.