CAS: 502612-54-6; (S)-6,7-Dihydro-5H-Cyclopenta[b]Pyridin-7-Amine
该化合物是化学化合物,其特点是双环结构,由环虫环组成,组成环虫圈;该化合物具有主要的安咪功能组,有助于其反应和潜在的生物活动;7S的命名表明,该化合物有特定的空间安排,可能影响其与生物目标的相互作用;通常,这种性质的化合物可能具有与药用化学有关的特性,包括在药物开发中或作为药剂使用的可能性;在环和矿组中存在氮原子,可以提高极地溶剂的溶性,也可以参与氢结合,影响化合物在生物系统中的整体行为;与许多含氮的外生循环一样,该混合物还可能表现出有趣的电子特性,使其在各个领域,包括有机合成和材料科学中成为人们感兴趣的主题.
- 英文名称(S)-6,7-Dihydro-5H-Cyclopenta[b]Pyridin-7-Amine
- 中文名称(S)-6,7-二氢-5H-环戊二烯[b]吡啶-7-胺
- IUPAC名称(S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine
- 其它别名(7S)-6,7-二氢-5H-7-氨基-环戊[b]并吡啶; (7S)-6,7-Dihydro-5H-Cyclopenta[b]Pyridin-7-Amine
- CAS编号502612-54-6
- MFCD编号:MFCD11558943
- 分子式:C8H10N2分子量:134.18
- 产品CID: 1489906
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
1932614-56-6 1187930-42-2 1228571-16-1MSDS等安全信息
上下游产品
6,7-二氢-5H-环戊并[b]吡啶-7-胺 6,7-Dihydro-5H-[1]Pyrindin-7-Ylamine 185122-75-2合成工艺路线路线简述
📜6,7-二氢-5H-环戊并[b]吡啶-7-胺置于candida Antarctica Lipase B,乙酸乙酯,盐酸体系中,化学反应 7.0H,反应生成 (R)-6,7-Dihydro-5H-[1]Pyrindin-7-Ylamine,(7S)-6,7-二氢-5H-环戊并[b]吡啶-7-胺
参考文献:Enzymatic Resolution Of Bicyclic 1-Heteroarylamines Using Candida Antarctica Lipase B
标题:Enzymatic Resolution Of Bicyclic 1-Heteroarylamines Using Candida Antarctica Lipase B
摘要:Candida Antarctica Lipase B Has Been Used To Kinetically Resolve A Structurally Diverse Series Of Bicyclic 1-Heteroaryl Primary Amines By Enantioselective Acetylation. High Yields Of Either Enantiomer Could Be Obtained With Excellent Enantioselectivity (90-99% Ee),While The Undesired Enantiomer Could,In Some Cases Be Recycled By Thermal Racemization. The Absolute Stereochemistry Of The Products Was Confirmed By An X-Ray Crystal Structure.
DOI:10.1021/jo026701R
海关参考信息
- 2933310010-吡啶
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7452994-B2
优先权日:2001-09-12
标 题 :Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
发明人：MCEACHERN ERNEST J; BRIDGER GARY J; SKUPINSKA KRYSTYNA A; SKERLJ RENATO T; YANG WEN
权利人:ANORMED INC
摘要:This invention describes various processes for synthesis and resolution of racemic amino-substituted fused bicyclic ring systems. One process utilizes selective hydrogenation of an amino-substituted fused bicyclic aromatic ring system. An alternative process prepares the racemic amino-substituted fused bicyclic ring system via nitrosation. In addition, the present invention describes the enzymatic resolution of a racemic mixture to produce the (R)- and (S)-forms of amino-substituted fused bicyclic rings as well as a racemization process to recycle the unpreferred enantioner. Further provided by this invention is an asymmetric synthesis of the (R)- or (S)-enantiomer of primary amino-substituted fused bicyclic ring systems.
专利号:US-2003114679-A1
优先权日:2001-09-12
标 题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
专利号:US-2005080267-A1
优先权日:2001-09-12
标 题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
专利号:US-2007060757-A1
优先权日:2001-09-12
标题 :Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
专利号:CA-2456614-A1
优先权日:2001-09-12
标题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
专利号:JP-2005508316-A
优先权日:2001-09-12
标题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
