CAS: 35249-89-9; Ammonium 2-Hydroxyacetate

📜氰基甲醇 甲醛氰醇置于immobilized E. Coli Mg1655/psw138-Phe168Val Nitrilaze Ammonium Hydroxide体系中,用99%的收率获得2-羟基乙酸铵
参考文献:化学酶法合成乙醇酸
标题:化学酶法合成乙醇酸
摘要:已经证明了用于生产高纯度乙醇酸的化学酶法,首先是甲醛与氰化氢反应以> 99%的收率和纯度生产乙醇腈.所得乙醇腈水溶液无需进一步纯化即可用于随后的乙醇腈向乙醇酸铵的生物催化转化.开发了一种基于acidovorax Facilis 72W腈水解酶的高活性生物催化剂,可在大肠杆菌中进行蛋白质工程设计和优化蛋白质表达与野生型菌株相比,转化宿主用于将微生物腈水解酶的比活性提高33倍.使用戊二醛/聚乙烯亚胺交联的角叉菜胶固定化表达mg.Facilis 72W腈水解酶突变体的大肠杆菌mg1655转化体,可实现> 1000 G乙醇酸/ G干细胞重量的生物催化剂生产力,连续产生3.2 M乙醇酸铵分批反应与生物催化剂循环使用,或在连续搅拌釜反应器中进行.通过在强酸阳离子树脂上进行固定床离子交换,可以将未纯化的乙醇酸铵产物溶液直接转化为高纯度乙醇酸水溶液.
Doi:10.1002/adsc.200700061

专利信息

专利号:US-5185378-A
优先权日:1990-10-01
标题:Iron-zinc catalysts for the conversion of synthesis gas to alpha-olefins
发明人：SOLED STUART L; MISEO SABATO; IGLESIA ENRIQUE; FIATO ROCCO A
权利人:EXXON RESEARCH ENGINEERING CO
摘要:New copper-potassium promoted iron-zinc catalysts wherein the iron:zinc atomic ratio is 5:1 or greater, exhibit improved activity, selectivity and stability in the synthesis of alpha-olefins from hydrogen and carbon monoxide.

专利号:US-5100856-A
优先权日:1990-10-01
标 题:Iron-zinc based catalysts for the conversion of synthesis gas to alpha-olefins
发明人：SOLED STUART L; MISEO SABATO; IGLESIA ENRIQUE; FIATO ROCCO A
权利人:EXXON RESEARCH ENGINEERING CO
摘要:New copper-potassium promoted iron-zinc catalysts wherein the iron:zinc atomic ratio is 5:1 or greater, exhibit improved activity, selectivity and stability in the synthesis of alpha-olefins from hydrogen and carbon monoxide.

专利号:WO-2009094936-A1
优先权日:2008-01-23
标题 :Catalyst for fischer-tropsch synthesis and its preparation method
发明人：BIAN GUOZHU; MAO HUAPING; HAN HUI; CONG PEIJUN
权利人:ACCELERGY SHANGHAI R & D CT CO; BP INTERNAT LTD; BIAN GUOZHU; MAO HUAPING; HAN HUI; CONG PEIJUN
摘要:In a method of making an iron-based catalyst for Fischer-Tropsch Synthesis with elements Fe, Mn, K, and Cu, a Fe, Mn nitrates solution is mixed with an ammonium glycolate or ammonium citrate solution to obtain a slurry material. The slurry material is processed to obtain a dry material, which is then impregnated with K and Cu to obtain a material containing Fe, Mn, K and Cu, which is further processed to obtain an iron based catalyst. The catalyst prepared by the method when applied in Fischer-Tropsch-Synthesis reactions can help achieve a high CO conversion and low CO2 selectivity for the reactions.

专利号:US-5118715-A
优先权日:1983-12-20
标 题:Selective fixed-bed fischer-tropsch synthesis with high surface area Cu and K promoted, iron/manganese spinels
发明人：IGLESIA ENRIQUE; SOLED STUART L; FIATO ROCCO A; BAUMGARTNER JOSEPH E
权利人:EXXON RESEARCH ENGINEERING CO
摘要:Pelletized, high surface area, Cu and Group IA or IIA dual metal promoted Mn-Fe spinels which are reduced and operated in a fixed-bed reactor provide exceptionally high catalytic activity and selectivity in the conversion of CO/H2 to high molecular weight hydrocarbons. These copper and Group IA or IIA metal promoted iron-manganese catalysts maintain good activity and selectivity to C5+ hydrocarbons, and give low selectivity to CO2.

专利号:EP-1833784-B1
优先权日:2004-12-22
标题:Process for the synthesis of glycolonitrile

专利号:WO-2006071663-A1
优先权日:2004-12-22
标题:Process for the synthesis of glycolonitrile