CAS: 26904-64-3; (41S,7As,13Ar,13Br)-10-Oxo-2,3,6,7,7A,8,10,13,13A,13B-Decahydro-1H,5H-Dipyrido[2,1-F:3',2',1'-Ij][1,6]Naphthyridine 4(41H)-Oxide
该化合物是一种化学化合物,主要来自Sophora Flavescens 植物,主要来自Sophora Flavescens 植物,主要来自该植物,以其结构特征著称,包括许多藻类的典型复杂的双环框架.该化合物展示了各种生物活动,包括潜在的抗炎和止痛作用,使其对药理学研究感兴趣.N-Oxysophoprocarpine已经研究过它对...
- 英文名称(41S,7As,13Ar,13Br)-10-Oxo-2,3,6,7,7A,8,10,13,13A,13B-Decahydro-1H,5H-Dipyrido[2,1-F:3',2',1'-Ij][1,6]Naphthyridine 4(41H)-Oxide
- 中文名称氧化槐果碱
- IUPAC名称(4S,41S,7aS,13aR,13bR)-10-oxo-2,3,6,7,7a,8,10,13,13a,13b-decahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide
- 其它别名Oxysophocarpine; (+)-Oxysophocarpine; (+)-Sophocarpine N-Oxide; Matridine-13-Ene-15-One 1-Oxide
- CAS编号26904-64-3
- MFCD编号:MFCD08689951
- EINECS号:683-162-0
- FDA UNII编号:58BVU7200M
- 分子式:C15H22N2O2分子量:262.35
- 产品CID: 1248510
- 产品分类生物化工 → 中草药成分
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号6483-15-4 槐果碱 | CAS号519-02-8 苦参碱合成工艺路线路线简述
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主要参考文献
1: Li L, Lu F, Ding S, Wang X, Wang W, Zhang W, Xu W, Zhuang C, Miao Z, Ma X. Pharmacokinetic, Tissue Distribution, Metabolite, and Toxicity Evaluation of the Matrine Derivative, (6aS, 10S, 11aR, 11bR, 11cS)-10-Methylaminododecahydro-3a, 7a-Diaza-benzo (de) Anthracene-8-thione. Molecules. 2024 Jan 6;29(2):297. doi: 10.3390/molecules29020297.
2: Liu C, Wang R, Jiao X, Zhang J, Zhang C, Wang Z. Oxysophocarpine suppresses TRAF6 level to ameliorate oxidative stress and inflammatory factors secretion in mice with dextran sulphate sodium (DSS) induced-ulcerative colitis. Microb Pathog. 2023 Sep;182:106244. doi: 10.1016/j.micpath.2023.106244. Epub 2023 Jul 7. 15(11):1384. doi: 10.3390/ph15111384.
4: Lin Y, Chen XJ, He L, Yan XL, Li QR, Zhang X, He MH, Chang S, Tu B, Long QD, Zeng Z. Systematic elucidation of the bioactive alkaloids and potential mechanism from Sophora flavescens for the treatment of eczema via network pharmacology. J Ethnopharmacol. 2023 Jan 30;301:115799. doi: 10.1016/j.jep.2022.115799. Epub 2022 Oct 8.
合成参考文献
参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
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