CAS: 261762-96-3; 2-(3-Chloro-2-Fluorophenyl)Acetic Acid

上下游产品

CAS号261762-98-5 3-氯-2-氟苯乙腈

📜3-氯-2-氟苯乙腈置于氢氧化钾,水,盐酸体系中,用 水 用作溶剂,化学反应 14.0H,反应生成3-氯-2-氟苯乙酸
参考文献:Aryl Fluoroethyl Ureas Acting As Alpha 2 Adrenergic Agents
标题:Aryl Fluoroethyl Ureas Acting As Alpha 2 Adrenergic Agents
摘要:本发明提供明确定义的芳基氟代乙基脲,用作选择性的α2肾上腺素能激动剂.因此,所述化合物可用于治疗与α2肾上腺素能受体调节相关的一系列疾病.

专利信息

专利号:US-11897857-B2
优先权日:2019-02-15
标 题 :Isotopically-stabilized tetronimide compounds
发明人：OLSEN MARK JON; SEERDEN JEAN PAUL
权利人:UNIV MIDWESTERN
摘要:Isotopically-stabilized tetronimide compounds comprising one or more deuterium atoms, derivatives, and intermediates, thereof, including methods for their synthesis, pharmaceutical compositions thereof, and methods of using these compounds to interact with target molecules in cell-free samples, cell- and tissue-based assays, animal models, and in a subject are disclosed. One aspect relates to molecules that modulate the expression or catalytic activity of aspartyl (asparaginyl) β-hydroxylase (ASPH) within or on the surface of a cell. Other aspects of the invention relate to use of the molecules disclosed herein to diagnose, ameliorate, or treat cell proliferation disorders and related diseases. Related aspects include uses of the compounds to modulate the activity of viruses, as anti-hyperlipidemia agents, and as agents to ameliorate or treat thrombosis and related cardiovascular and metabolic disorders.