CAS: 17357-14-1; 5-Bromo-1H-Indol-3-Yl Acetate

上下游产品

CAS号10075-50-0 5-溴吲哚 | CAS号3240-34-4 碘苯二乙酸 | CAS号33588-54-4 5-溴羟基吲哚二乙酸酯

📜5-溴吲哚置于碘,Potassium Iodide,Sodium Hydroxide体系中,用 甲醇,水,溶剂黄146 用作溶剂,化学反应 4.0H,反应生成5-溴代-3-羟基吲哚乙酸酯
参考文献:High Performance Ambipolar Organic Field-Effect Transistors Based On Indigo Derivatives
标题:High Performance Ambipolar Organic Field-Effect Transistors Based On Indigo Derivatives
摘要:仿生有机半导体5,5'-二苯基靛蓝显示出优异且均衡的双极晶体管特性;其空穴和电子迁移率分别为0.56和0.95 Cm2 V−1 S−1.性能的增强归因于苯基基团的扩展π-π重叠以及人字形和砖砌结构混合的特征堆积模式.考虑其工作区域来分析双极晶体管的特性,其中由于电子和空穴阈值电压的差异而出现大的单极饱和区域.
Doi:10.1039/c4Tc01563K

专利信息

专利号:US-6303764-B1
优先权日:1998-09-24
标题:Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
发明人：SRIVASTAVA OM; SRIVASTAVA GEETA; DU MINGHUI; HINDSGAUL OLE; BUNDLE DAVID R; LIAV AVRAHAM
权利人:ZYMETX INC; HALIFEX FUND L P
摘要:The present invention provides an improved method of preparing a 4,7-di-O-alkyl chromogenic ketoside of N-acetylneuraminic acid (Neu5Ac) for use in detecting influenza virus types A and B. The ketosides are substrates that are selectively cleaved by a neuraminidase on influenza virus, but not be neuraminidases found on other viruses or on bacteria. The synthesis is efficient and provides large quantities of the ketoside for commercial development. The synthesis includes a step of alkylating the 4- and 7-hydroxyl groups of a protected alkyl ester alkyl ketoside derivative of Neu5Ac by a process that comprises contacting the derivative with a composition comprising an alkyl halide to form a 4,7-di-O-alkyl protected alkyl ester alkyl ketoside derivative of Neu5Ac. The synthesis alternatively includes protecting the 8- and 9-hydroxyl groups of an alkyl ester alkyl ketoside derivative of Neu5Ac by forming an 8,9-epoxide protected alkyl ester alkyl ketoside derivative of Neu5Ac.

专利号:US-6420552-B1
优先权日:1999-09-10
标题:Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
发明人：SRIVASTAVA OM; SRIVASTAVA GEETA; DU MINGHUI; HINGSGAUL OLE; BUNDLE DAVID R
权利人:ZYMETX INC
摘要:The present invention provides improved method of preparing a 4-O-alkyl chromogenic ketoside of N-acetylneuraminic acid (Neu5Ac) and a 7-O-alkyl chromogenic ketoside of N-acetylneuraminic acid (Neu5Ac) for use in the selective detection of various influenza viruses and parainfluenza viruses. The ketosides are substrates that are selectively cleaved by a neuraminidase on the virus to be detected, but not by neuraminidases found on other viruses or on bacteria, or on the cells of the host. The syntheses are efficient and provide large quantities of the ketosides for commercial development. The synthesis includes a step of alkylating the 4- or 7-hydroxyl groups of a protected alkyl ester alkyl ketoside derivative of Neu5Ac by processes that include contacting the derivative with a composition comprising an alkyl halide to form a 4- or a 7-O-alkyl protected alkyl ester alkyl ketoside derivative of Neu5Ac. The syntheses alternatively include protecting the 8- and 9-hydroxyl groups of an alkyl ester alkyl ketoside derivative of Neu5Ac by forming an 8,9-ketal or an 8,9-epoxide protected alkyl ester alkyl ketoside derivative of Neu5Ac.