CAS: 1439-07-2; Trans-2,3-Diphenyloxirane

该化合物是一种有机过氧化化合物,具有分子式C14H12O.由于结构僵硬和立体化学特性,该化合物被广泛用作非对称合成和制药研究中的一个手动建筑块.该化合物是制作光学活性化合物的关键中间体,利用其进行重生选择性环开反应的能力.其高纯度和稳定性使其适合用于催化研究和材料科学应用.此外,跨二丁氧物因其定义明确的化学行为和在实验环境中的再生性,被作为染色谱分析和光谱研究的标准.

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    专利信息


    专利号:US-10801033-B2
    优先权日:2016-04-05
    标题 :Recombinant polynucleotide involved in lactone synthesis and process for synthesis of lactones thereof
    发明人:GUPTA VIDYA SHRIKANT; DESHPANDE ASHISH BALWANT; OAK PRANJALI SUDHIR; GIRI ASHOK PRABHAKAR
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention provides the polynucleotide encoding enzyme involved in lactone synthesis and a process for synthesis of lactones using said polynucleotides. The invention also provides recombinant plasmid expression vector comprising said polynucleotide sequence. The recombinant protein encoded by said polynucleotides leads to synthesis of lactones having flavour peculiar to Alphonso mangoes.

    专利号:US-10799441-B2
    优先权日:2011-06-06
    标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
    发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
    权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
    摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

    专利号:US-11773060-B2
    优先权日:2016-05-25
    标题 :Method for synthesis of 9-cis-beta-carotene and formulations thereof
    发明人:GAZIT EHUD; BUZHANSKY LUDMILA; IOFFE MICHAEL; SAYER ALON
    权利人:UNIV RAMOT
    摘要:A formulation includes an active agent, a thickening/solidifying agent, and an antioxidant. The active agent is 9-cis-β-carotene (9CBC) or a derivative thereof of the following formula:where R2 is H or methyl; X isoptionally substituted with one or more methyl groups; n is an integer of 0-16; and the asterisk represents the point of attachment to the cyclohexene ring.

    专利号:US-8921580-B2
    优先权日:2012-05-09
    标 题 :Methods and systems for the formation of cyclic carbonates
    发明人:HATTON TREVOR ALAN; JAMISON TIMOTHY F; KOZAK JENNIFER AIDEN; SIMEON FRITZ; WU JIE
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:Described herein are inventive methods for synthesis of cyclic carbonates from CO 2 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the methods are carried out in a flow reactor.

    专利号:US-7825240-B2
    优先权日:1998-09-11
    标题:Cross-linked polymers based on bis-silane, bis-thioether, bis-sulphoxide, bis-sulphone and butane-di-yl derivatives of polysaccharides and oligosaccharides, and their shaping as support materials
    发明人:DUVAL RAPHAEL
    权利人:EKA CHEMICALS AB
    摘要:There are described novel cross-linked polymers based on bis-silane, bis-thioether, bis-sulphoxide, bis-sulphone and butane-di-yl derivatives of polysaccharides and oligosaccharides, their shaping as support materials useful for the separation or preparation of enantiomers; a process for preparing the said cross-linked polymer compounds, a process for preparing balls of support materials containing the said cross-linked polymer compounds; a method of obtaining balls of support materials useful in chromatography or in organic synthesis; and the use of the said support materials containing the cross-linked polymer compounds in separation or in preparation of enantiomers, through employment in chromatography or organic synthesis processes in a heterogeneous medium; and the use of the said cross-linked polymer compounds in the form of membranes in processes using percolation through membranes for the separation or the preparation of enantiomers.

    专利号:US-7825268-B2
    优先权日:2003-12-23
    标 题:Alkoxylactones, alkoxylactams and alkoxythiolactams for controlling processes based on microbial interaction
    发明人:STUMPE STEFAN; BREVES ROLAND; HUCHEL URSULA; JANSSEN FRANK; HAETZELT ANDRE
    权利人:HENKEL AG & CO KGAA
    摘要:Compounds of the Formula I, n nwherein A 1 is O or NH; A 2 is O or S; each of R 1 and R 2 is independently hydrogen, a methyl or C 2 -C 8 -saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group; and R 3 is a C 1 -C 18 -saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group wherein, each of R 1 , R 2 and R 3 comprises a heteroatom selected from the group consisting of O and S in the chain and/or is mono- or multiply-substituted by a substituent selected from the group consisting of halogen, hydroxy, C 1 -C 6 -alkyl, trifluoromethyl, C 1 -C 6 -alkoxy, C 6 -C 10 -aryl, and C 1 -C 6 -alkyl-C 6 -C 10 -aryl are useful for controlling the interaction process between microorganisms such as in the development and/or maturation of biofilms; multicellular swarm behavior; the concerted development of antibiotic resistances; the concerted synthesis of antibiotics; the concerted synthesis of pigments; the concerted production of extracellular enzymes; or the concerted production of virulence factors.

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    主要参考文献

    [参考文献]: A L Slitt, Et Al. Induction Of Genes For Metabolism And Transport By Trans-Stilbene Oxide In Livers Of Sprague-Dawley And Wistar-Kyoto Rats. Drug Metab Dispos. 2006 Jul;34(7):1190-7.
    [参考文献]: A L Slitt, Et Al. Induction Of Multidrug Resistance Protein 3 In Rat Liver Is Associated With Altered Vectorial Excretion Of Acetaminophen Metabolites. Drug Metab Dispos. 2003 Sep;31(9):1176-86.
    [参考文献]: Endang R Purba, Et Al. The Metabolism Of Lysophosphatidic Acids By Allelic Variants Of Human Soluble Epoxide Hydrolase. Drug Metab Pharmacokinet. 2015 Feb;30(1):75-81.
    [参考文献]: Joel Putnam, Et Al. A Test To Determine The Nature And Presence Of The Memory Effect Columns Packed With The Amylose Tris(3,5-Dimethylphenylcarbamate) Stationary Phase. J Chromatogr A. 2011 Sep 16;1218(37):6302-7.
    [参考文献]: Joel Putnam, Et Al. The Influence Of The Memory Effect On Preparative Separations Using The Amylose Tris(3,5-Dimethylphenylcarbamate) Stationary Phase. J Chromatogr A. 2011 Aug 5;1218(31):5157-65.

    合成参考文献


    摘要:Xia, F.; Ye, S., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 7.
    摘要:Ciszek, B.; Fleischer, I., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 177.
    参考文献:10.1007/bf00400749
    摘要:Frei E, Pool BL, Glatt HR, Gemperlein-Mertes I, Oesch F, Schlehofer JR, Schmezer P, Weber H, Wiessler M. Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities. Journal of Cancer Research and Clinical Oncology. 1986 Apr;111(2):123–8. doi: 10.1007/bf00400749.
    参考文献:10.1007/s00253-006-0569-1
    摘要:Yamada M, Okada Y, Yoshida T, Nagasawa T. Biotransformation of isoeugenol to vanillin by Pseudomonas putida IE27 cells. Applied Microbiology and Biotechnology. 2006 Aug 30;73(5):1025–30. doi: 10.1007/s00253-006-0569-1.
    参考文献:10.2478/s11658-008-0022-9
    摘要:Billack B, Radkar V, Adiabouah C. In Vitro evaluation of the cytotoxic and anti-proliferative properties of resveratrol and several of its analogs. Cellular & Molecular Biology Letters. 2008 May 30;13(4):553–69. doi: 10.2478/s11658-008-0022-9.
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