CAS: 135795-46-9; 3-Amino-2-Bromo-6-Methoxypyridine

相似化合物

344296-05-5 89466-18-2 53242-18-5

上下游产品

6-methoxy-pyridin-3-ylamine 2-bromo-6-methoxy-3-nitropyridine 5-Ethyl-7-(3-methoxy-phenyl)-10-methyl-5,10-dihydro-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one 7-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-5-ethyl-10-methyl-5,10-dihydro-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one 7-(6-Benzylamino-pyridin-3-yl)-5-ethyl-10-methyl-5,10-dihydro-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one [4-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-7-yl)-phenyl]-carbamic acid tert-butyl ester

📜5-氨基-2-甲氧基吡啶置于benzyltrimethylazanium Tribroman-2-Uide体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 24.0H,反应生成3-氨基-6-甲氧基-2-氯吡啶
参考文献:1N-Alkyl-N-Arylpyrimidinamines And Derivatives Thereof
标题:1N-Alkyl-N-Arylpyrimidinamines And Derivatives Thereof
摘要:本发明提供了新颖的化合物,该化合物及其药物组合物,以及在治疗情感障碍,焦虑,抑郁,创伤后应激障碍,进食障碍,上核性麻痹,肠易激综合征,免疫抑制,阿尔茨海默病,胃肠疾病,厌食症,药物和酒精戒断症状,药物成瘾,炎症性疾病或生育问题中使用这些方法.本发明提供的新型化合物为以下公式的化合物: 其中r1,R3,R4,R5,Z,Y,V,X,X',J,K,L和m如本文所定义.

专利信息

专利号:US-8987195-B2
优先权日:2012-08-08
标 题:HCV NS3 protease inhibitors
发明人：BARA THOMAS; BHAT SATHESH; BISWAS DIPSHIKHA; BROCKUNIER LINDA; BURNETT DUANE A; CHACKALAMANNIL SAMUEL; CHELLIAH MARIAPPAN V; CHEN AUSTIN; CLASBY MARTIN; COLANDREA VINCE J; GUO ZHUYAN; HAN YONGXIN; JAYNE CHARLES; JOSIEN HUBERT; MARCANTONIO KAREN; MIAO SHOUWU; NEELAMKAVIL SANTHOSH; PINTO PATRICK; RAJAGOPALAN MURALI; SHAH UNMESH; VELAZQUEZ FRANCISCO; VENKATRAMAN SRIKANTH; XIA YAN
权利人:MERCK SHARP & DOHME; MERCK CANADA INC
摘要:The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.