CAS: 1187586-58-8; [r,E]-[[1-[3-[2-(7-Chloro-2-Quinolinyl)-2-(R)-[(Carboxymethyl)Cyclopropyl]Methyl]Thio]Ethyl]Phenyl]-3-[[[[2-(1-Hydroxy-1-Methylethyl)Phenyl]Propyl]Thio]Methyl]-Cyclopropane Acetic Acid

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1-(sulfanylmethyl)cyclopropaneacetic acid Montelukast sodium [R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-[1-(1-methyl)ethenyl]phenyl]propyl]thio]methyl]cyclopropaneacetic acid 41H44ClNO4S2C41H44ClNO4S2

📜2-[2-[3(S)-[3-(7-氯-2-喹啉基)乙烯基]苯基]-3-羟基丙基]苯基-2-丙醇置于盐酸,4-二甲氨基吡啶,硫酸,水,Sodium Methylate,对甲苯磺酸,三乙胺,N,N-二异丙基乙胺,Sodium Hydroxide体系中,用 四氢呋喃,甲醇,二氯甲烷,水,乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,化学反应 29.5H,反应生成[r,E]-[[1-[3-[2-(7-Chloro-2-Quinolinyl)-2-(S)-[(Carboxymethyl)Cyclopropyl]Methyl]Thio]Ethyl]Phenyl]-3-[[[[2-(1-Hydroxy-1-Methylethyl)Phenyl]Propyl]Thio]Methyl]-Cyclopropane Acetic Acid,1-[[[(1R)-1-[3-[(1S)-1-[[[1-(羧甲基)环丙基]甲基]硫基]-2-(7-氯-2-喹啉基)乙基]苯基]-3-[2-(1-羟基-1-甲基乙基)苯基]丙基]硫基]甲基]环丙烷乙酸
参考文献:Sunil Kumar; Anjaneyulu; Hima Bindu,Asian Journal Of Chemistry,2011,Vol. 23,# 10,P. 4536-4546
标题:Sunil Kumar; Anjaneyulu; Hima Bindu,Asian Journal Of Chemistry,2011,Vol. 23,# 10,P. 4536-4546