CAS: 94367-20-1; N-Succinyl-Leu-Tyr-7-Amido-4-Methylcoumarin
该化合物是一个复杂的有机化合物,其独特的结构包括氨酸残留物和苯丙胺酸混合物.该化合物具有一个碳boxylic酸化合物组,它有助于极地溶剂中的潜在溶性,并且是一种常见于peptide化学中的粘合物.苯丙基环的存在表明潜在的生物活动,因为含有这种结构的许多化合物的抗氧化剂和抗炎特性是众所周知的.
- 英文名称N-Succinyl-Leu-Tyr-7-Amido-4-Methylcoumarin
- 中文名称N-琥珀酰基-亮氨酰-酪氨酸-7-胺基-4-甲基香豆素
- 其它别名SUCCINYL-LEU-TYR-AMC; SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN; SUC-LEU-TYR-AMC; SUC-LY-AMC; N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE; N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN; CALPAIN SUBSTRATE I; CALPAIN SUBSTRATE II, FLUOROGENIC
- CAS编号94367-20-1
- MFCD编号:MFCD00057900
- 分子式:C29H33N3O8分子量:551.59
- 产品CID: 1993898
- 产品分类生物化工 → 氨基酸及其衍生物 → 酪氨酸类衍生物
物理性质
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5514694-A
优先权日:1992-09-21
标题 :Peptidyl ketoamides
发明人：POWERS JAMES C; LI ZHAOZHAO; PATIL GIRISH S; CHU DER-LUN
权利人:GEORGIA TECH RES INST
摘要:A novel class of peptide alpha -ketoamides useful for selectively inhibiting serine proteases, selectively inhibiting cysteine proteases, generally inhibiting all serine proteases, and generally inhibiting all cysteine proteases, having the formula Y-CO-AA2-AA1-CO-NH-X. Processes for the synthesis of peptidyl alpha -ketoamide derivatives.
专利号:US-8518885-B2
优先权日:2008-02-06
标题 :Heterocyclic peptide ketoamides
发明人：POWERS JAMES C; GLASS JONATHAN D; OVAT ASLI; LI ZHAOZHAO
权利人:POWERS JAMES C; GLASS JONATHAN D; OVAT ASLI; LI ZHAOZHAO; GEORGIA TECH RES INST; UNIV EMORY
摘要:A novel class of peptide α-ketoamides useful for selectively inhibiting calpains, selectively inhibiting cysteine proteases, and generally inhibiting all cysteine proteases, having the formula M-AA 2 -AA 1 -CO—NH—(CH 2 ) n —R 3 . Processes for the synthesis of peptidyl α-ketoamide derivatives. Compositions and methods for inhibiting cysteine proteases, inhibiting calpains, and treating disease caused by cysteine proteases and calpains are provided.
