CAS: 6236-09-5; (S)-2-Hydroxy-2-Methylsuccinic Acid

相似化合物

77-92-9 77-92-9 5949-29-1

上下游产品

CAS号498-24-8 中康酸 | CAS号93239-42-0 (R)-(+)-4-甲基-4-... | CAS号32814-34-9 3-Furoicacid,te... | CAS号32814-35-0 (+/-)-Methyl-γ-... | CAS号597-44-4 2-hydroxy-2-met... | CAS号104194-10-7 1,3-Dioxolan-4-... | CAS号58109-21-0 methyl 5,6-O-cy... | CAS号32150-78-0 (4S)-(+)-4-meth... | CAS号62875-07-4 2-甲基-1,2,4-丁烷三醇

📜中康酸置于聚合甲醛,四环素,Paraquat Dichloride体系中,用 水 作为反应溶剂,化学反应 24.0H,以69.8%的收率获得产物(S)-(+)-柠苹酸
参考文献:通过顺式或反式2-丁烯-1,4-二酸与福尔摩斯氏梭菌的静息细胞立体定向水合制备苹果酸和柠檬酸对映体以及其他羟基琥珀酸衍生物
标题:通过顺式或反式2-丁烯-1,4-二酸与福尔摩斯氏梭菌的静息细胞立体定向水合制备苹果酸和柠檬酸对映体以及其他羟基琥珀酸衍生物
摘要:(R)-苹果酸,(S)-苹果酸,(R)柠檬酸,(S)-柠檬酸,(2 R,3 S)-2-羟基-3-甲基-琥珀酸和(2 R,3 S)-2通过将水立体定向加成到不同的2-丁烯-1,4-二酸衍生物中,由梭状梭状芽孢杆菌的静止细胞催化,可制备高达25 Mmol的规模的3-3-二甲基-2-羟基琥珀酸(方案1).的(3-[r)-Monodeuterio([r)-和(小号)-苹果酸,以及(-[r)-和(小号)-Citramalic苯甲酸用冷冻干燥的细胞中制备的2H2O缓冲区.在大多数情况下,产品的立体化学纯度均>=99%.
DOI:10.1016/s0040-4020(01)85678-7

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-4668822-A
优先权日:1985-04-15
标 题:Method for preparing (+)S-2--hydroxy-2-methyl-hexanoic acid
发明人：COREY PAUL F
权利人:MILES LAB
摘要:A method for preparing an important stereo-specific intermediate in the synthesis of prostaglandin analogs is disclosed. Said intermediate is (+)S-2-hydroxy-2-methyl-hexanoic acid and is prepared via an asymmetric halolactonization reaction utilizing L-proline as the chiral agent.

专利号:US-4633025-A
优先权日:1985-04-15
标 题:Method for preparing (+)R-2-methyl-hexane-1,2-diol
发明人：COREY PAUL F
权利人:MILES LAB
摘要:A method for preparing important stereospecific intermediates in the synthesis of prostaglandin analogs is disclosed. Said intermediates are (+)R-2-methyl-hexane-1,2-diol and (-)S-2-methyl-hexane-1,2-diol and are prepared via an asymmetric halolactonization reaction utilizing L-proline and D-proline, respectively as the chiral agent.

专利号:CN-109722444-A
优先权日:2019-01-02
标 题 :A kind of recombinant plasmid pZQ12, the recombinant bacterium of synthesis odevity carbochain monomer copolymerization mcl-PHA and its application

专利号:WO-2009007660-A1
优先权日:2007-07-04
标题:Liquid or paste compositions intended to provide elements essential for the synthesis and formation of proteoglycans, in particular, for the treatment of cartilage degradation

专利号:FR-2918376-A1
优先权日:2007-07-04
标题 :LIQUID OR PASSIZED COMPOSITIONS FOR THE CONTRIBUTION OF ESSENTIAL ELEMENTS TO THE SYNTHESIS AND CONSTITUTION OF PROTEOGLYCANS, IN PARTICULAR FOR THE TREATMENT OF CARTILAGE DEGRADATION