专利号:US-2003138490-A1 优先权日:2001-09-08 标 题 :Synthesis and uses of polymer gel nanoparticle networks 发明人:HU ZHIBING; LU XIHUA; GAO JUN; PONDER BILL C; JOHN JOHN ST; MORO DANIEL G 摘要:Disclosed is a new class of nanostructured polymeric materials comprising polymer gel nanoparticles that are covalently bonded through functional groups on the surfaces of neighboring particles. These nanoparticles may be prepared as suspensions in an aqueous or, non-aqueous environment. These gels have two unique and different structural networks; the primary network comprises crosslinked polymer chains in each individual particle, while the secondary network is a system of crosslinked nanoparticles. Particular polymer gel nanoparticle network compositions disclosed herein may function as carriers for controlled delivery of pharmaceuticals or other chemical agents, gel sensors and other commercial applications.
专利号:US-2013030282-A1 优先权日:2011-07-18 标题:Synthesis and characterization of near ir fluorescent magnetic and non-magnetic albumin nanoparticles for biomedical applications 发明人:MARGEL SHLOMO; COHEN SARIT; SALKMON ENAV COREM; PELLACH MICHAL 权利人:UNIV BAR ILAN; MARGEL SHLOMO; COHEN SARIT; SALKMON ENAV COREM; PELLACH MICHAL 摘要:The present invention discloses Near Infrared (NIR) fluorescent albumin nanoparticles having a structure selected from a core structure or a core-shell structure. Also disclosed are a process of preparing these NIR fluorescent albumin nanoparticles, and a method of in vivo detection of pathologies, in particular cancer pathology, by using administering these NIR fluorescent albumin nanoparticles to a patient.
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:WO-03022910-A1 优先权日:2001-09-08 标题:Synthesis and uses of polymer gel nanoparticle networks
1: Fujimura A, Ebihara A, Hino N, Koike Y. Effects of traxanox sodium on blood pressure and serum uric acid in hypertensive patients: a preliminary study. J Clin Pharmacol. 1989 Apr;29(4):327-30. Japanese. 6: Terasawa M, Imayoshi T, Maruyama Y, Abe C. [Effect of traxanox sodium on inflammatory response]. Nihon Yakurigaku Zasshi. 1985 Nov;86(5):329-40. Japanese. Japanese. Japanese. Japanese. Japanese. Japanese.
合成参考文献
参考文献:10.1254/fpj.86.329 摘要:Terasawa M, Imayoshi T, Maruyama Y, Abe C. [Effect of traxanox sodium on inflammatory response]. Nihon Yakurigaku Zasshi. 1985 Nov;86(5):329–40. doi: 10.1254/fpj.86.329. 摘要:United States Patent Document., #4555510