CAS: 5429-28-7; 4-Diethylaminobenzoic Acid

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CAS号120-21-8 N,N-二乙基-4-氨基苯甲醛 | CAS号65613-24-3 p-Diethylamino-... | CAS号655-32-3 2,2,2,4'-四氟苯乙酮 | CAS号103-69-5 N-乙基苯胺 | CAS号91-66-7 N,N-二乙基苯胺 | CAS号150-13-0 对氨基苯甲酸 | CAS号75-03-6 碘乙烷 | CAS号75-44-5 光气 | CAS号124-38-9 二氧化碳 | CAS号2052-06-4 4-溴-N,N-二乙基苯胺 | CAS号3846-50-2 2,4-二硝基-N-乙基苯胺 | CAS号837-64-9 2,4-二硝基-N,N-二乙基苯胺 | CAS号2788-74-1 4-(Ethylamino)-... | CAS号7449-27-6 N-ethyl-2,4,6-t... | CAS号10287-54-4 4-(N,N-二乙基氨基)苯甲酸乙酯 | CAS号100139-54-6 4-(三乙基胺)苯酰肼 | CAS号2216-15-1 N,N-二乙基-4-硝基苯胺 | CAS号65072-47-1 4-(diethylamino... | CAS号91182-00-2 4-ETHYLAMINO-3-... | CAS号91563-80-3 4-二乙氨基苯甲酸甲酯

📜2,2,2,4'-四氟苯乙酮置于sodium Hydroxide,三乙胺体系中,用 二甲基亚砜,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 2.5H,反应生成 4-(N,N-二乙氨基)-苯甲酸
参考文献:一种制备 4-氮取代苯甲酸的实用方法
标题:一种制备 4-氮取代苯甲酸的实用方法
摘要:描述了一种有效且实用的制备 4-氮取代苯甲酸的方法.我们的方法包括 2,2,2,4'-四氟苯乙酮与胺的芳香取代,然后是苯甲酸的卤仿反应.在该方法中,即使对于亲核性较低的 7-,8-和 9-元胺 1 当量.使用时,相应的苯甲酸以中等至极好的收率获得.由于包括纯化在内的实验步骤简单,该方法适用于大规模合成.
DOI:10.1246/cl.2006.1090

专利信息

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:CN-101531680-A
优先权日:2008-03-13
标 题:Synthesis of (R)-9-[2-(diethylphosphonomethoxy)propyl]-adenine

专利号:CN-101531680-B
优先权日:2008-03-13
标题:Synthesis of (R)-9-[2-(diethylphosphonomethoxy)propyl]-adenine

专利号:CN-107673998-A
优先权日:2017-10-11
标 题:A kind of green synthesis method of 1,4-bis(o-cyano-styryl)benzene