CAS: 39257-91-5; Methyl 4-Mercaptobutanoate

该化合物是一种含有含有分子式C5H10O2S的硫酸酯.该化合物的特征是其硫基(硫醇)功能组,该组在有机合成和口味/香味应用中具有有用的再活性.其结构将酯酶与终端硫醇结合起来,能够参与分子分子式C5H10O2S等核生殖反应,并成为更复杂的硫基分子的前体.该化合物的挥发性和独特的气味特征使其与芳香化学有关,因为它可能有助于水果或香味的笔记.由于硫醇组的潜在再活动及其氧化敏感性,建议谨慎处理.

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Thiobutyrolactone methanol sodium methylate p-xylylenedisulfonyl-di-butyric acid dimethyl ester4,4'-p-xylylenedisulfonyl-di-butyric acid dimethyl ester methyl 4-(2-formylphenylthio)butyrate (+/-) methyl 4-[(3-{4-chlorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}propyl)thio]butyrate 4-[bis-(4-methoxy-phenyl)-phenyl-methylsulfanyl]-butyric acid methyl ester

合成工艺路线路线简述

    📜γ--硫代丁内酯置于三乙胺体系中,用 甲醇 用作溶剂,化学反应 24.0H,反应生成阿哌沙班杂质61
    参考文献:Studies Directed Towards The Total Synthesis Of Dicyclopenta[a,D]Cyclooctane Terpenoids
    标题:Studies Directed Towards The Total Synthesis Of Dicyclopenta[a,D]Cyclooctane Terpenoids
    摘要:
    Doi:10.1016/s0040-4020(01)81706-3

    海关参考信息

    专利信息


    专利号:US-2024417420-A1
    优先权日:2021-10-04
    标题:Polar cd33 ligands suitable for incorporation into carriers
    发明人:MAGNANI JOHN L; PETERSON JOHN M; GHOSH LNDRANATH; NOGUEIRA JASON; RAHMAN MITI
    权利人:GLYCOMIMETICS INC
    摘要:CD33 ligands which are useful for the synthesis of CD33 ligand-bearing carriers, wherein said CD33 ligand-bearing carriers are directly or indirectly linked to or associated with at least one anti-cancer agent, are described herein. Uses of said CD33 ligand-bearing carriers for treating and/or preventing a disease, disorder, or condition such as acute myeloid leukemia (AML) are also described.

    专利号:US-4018820-A
    优先权日:1970-07-09
    标题 :Chemical synthesis
    发明人:FRIED JOSEF
    权利人:UNIV CHICAGO
    摘要:This invention relates to pharmacologically active compounds of the formula: ##STR1## wherein Z is trans-CH=CH, C.tbd.C; or CH 2 -CH 2 ; n M is H or lower alkyl; n n is an integer of from 2 to 5; n X is alkyl; n W is H or OR, wherein R is H, acyl, or alkyl; and n Each Y is H, OH or alkoxy; n And to novel intermediates and processes useful in the production thereof.

    专利号:US-4175201-A
    优先权日:1973-05-18
    标 题 :Chemical synthesis
    发明人:FRIED JOSEF
    权利人:CHICAGO UNIVERSITY
    摘要:This invention relates to pharmacologically active compounds of the formula: ##STR1## wherein Z is trans--CHâ•?CH, C.tbd.C; or CH 2 --CH 2 ; n M is H or lower alkyl; n n is an integer of from 2 to 5; n X is alkyl; n W is H or OR, wherein R is H, acyl, or alkyl; n each Y is H, OH or alkoxy; n and to novel intermediates and processes useful in the production thereof.

    专利号:US-11732283-B2
    优先权日:2016-06-24
    标 题 :Nucleic acid synthesis and sequencing using tethered nucleoside triphosphates
    发明人:ARLOW DANIEL; PALLUK SEBASTIAN
    权利人:UNIV CALIFORNIA
    摘要:Provided herein, among other things, is a conjugate comprising a polymerase and a nucleoside triphosphate, where the polymerase and the nucleoside triphosphate are covalently linked via a linker that comprises a cleavable linkage. A set of such conjugates, where the conjugates correspond to G, A, T (or U) and C is also provided. Methods for synthesizing a nucleic acid of a defined sequence are also provided. The conjugates can also be used for sequencing applications.

    专利号:WO-2023115040-A2
    优先权日:2021-12-16
    标 题:Methods of polynucleotide synthesis

    专利号:WO-2023115047-A2
    优先权日:2021-12-16
    标 题:Compositions for enzymatic polynucleotide synthesis and methods of use

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1055/s-0029-1219301
    摘要:Synthesis of ONO-4819. Synfacts. 2010 Feb 18;2010(03):0267. doi: 10.1055/s-0029-1219301.
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