CAS: 335654-06-3; 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine

相似化合物

2347374-92-7 1060815-90-8 1638768-28-1

上下游产品

CAS号335654-05-2 2-氯-5-(2-乙氧基乙烯基... | CAS号90213-66-4 2,4-二氯-7H吡咯[2,3-D]嘧啶 | CAS号335654-13-2 2-chloro-5-(2,2... | CAS号322728-22-3 1H-吡咯并[2,3-d]嘧啶... | CAS号67-56-1 甲醇 | CAS号335654-08-5 2-氯-5H-吡咯并[2,3-... | CAS号1060815-90-8 2-氯-5-碘-7H-吡咯并[... | CAS号93366-88-2 7H-吡咯并[2,3-D]嘧啶-2-胺 | CAS号5817-96-9 5,7-二氢-6H-吡咯并[2...

2,4-二氯-7H吡咯[2,3-D]嘧啶置于溶剂黄146,锌体系中,用 甲醇 用作溶剂,化学反应 16.0H,以63.86%的收率获得2-氯-7H-吡咯并[2,3-D]嘧啶
参考文献:一种嘧啶并环中选择性脱卤素的方法
标题:一种嘧啶并环中选择性脱卤素的方法
摘要:本发明公开了一种嘧啶并环中选择性脱卤素的方法,该方法通过锌粉和乙酸溶液的加热反应,可对嘧啶环上的卤素进行选择性脱卤,维持嘧啶环和并环上的原取代基.该方法的操作步骤少,收率高,适用于规模化生产.

专利信息

专利号:US-2022315594-A1
优先权日:2019-08-09
标 题 :Method of synthesis of compound for dual inhibition of jak2 and bet
发明人：UPADHAYAYA RAM SHANKAR; UKKALAM MURALI KRISHNA; SARMA K NARASIMHA
权利人:OHM ONCOLOGY
摘要:Embodiments of the invention include quinoline compounds and methods of synthesis. Ohm-581 has demonstrated dual inhibition of JAK2 and BET and acts as a therapeutic agent for micosis fungoides (MF) and other hematologic malignancies. Embodiments also include an efficient process for the preparation of Ohm-581 and pharmaceutically acceptable salts. The process is suited for large-scale production of quinoline compounds including Ohm-581.

专利号:WO-2008148560-A1
优先权日:2007-06-07
标题 :New hybrid compounds of nucleobases and organic redox molecules and their use
发明人：ASAFTEI SIMONA CARMEN
权利人:UNIV OSNABRUECK; ASAFTEI SIMONA CARMEN
摘要:The present invention relates to new compounds as well as methods for the synthesis of the same, said compounds comprise a redox active group, e.g. a 4,4-bipyridine (viologen), a 1,2-di(4-pyridyl)ethane, a 2,7-diazapyrene or 2,9-diazaperylene group and a N-heterocyclic nucleobase (HB), also referred to as base.

专利号:WO-2021030238-A2
优先权日:2019-08-09
标题:Method of synthesis of compound for dual inhibition of jak2 and bet

专利号:CN-109608468-A
优先权日:2018-12-29
标 题 :A kind of tofacitinib citrate impurity and its synthesis method and use

专利号:CN-108699063-A
优先权日:2015-12-31
标题 :Synthesis process of luccotinib

专利号:CN-118406056-A
优先权日:2023-01-28
标 题:A kind of aza-2-indolone derivative and its synthesis method