CAS: 23282-20-4; Nivalenol

上下游产品

4β,15-Diacetylnivalenol3-hemisuccinylnivalenol 3,4-dihemisuccinylnivalenol 3,15-diacetylnivalenol 15-acetylnivalenol

📜4,15-Diacetylnivalenol置于甲醇,Sodium Hydroxide体系中,化学反应 0.67H,反应生成雪腐镰刀菌烯醇
参考文献:Grove,John Frederick,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 1731-1736
标题:Grove,John Frederick,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 1731-1736

专利信息

专利号:US-8912150-B2
优先权日:2001-08-03
标题:Ribosome structure and protein synthesis inhibitors
发明人：STEITZ THOMAS A; MOORE PETER B; SUTCLIFFE JOYCE A; OYELERE ADEGBOYEGA K; IPPOLITO JOSEPH A
权利人:RIB X PHARMACEUTICALS INC; UNIV YALE; MELINTA THERAPEUTICS INC
摘要:The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.

专利号:US-2022249576-A1
优先权日:2021-02-09
标 题:Method of disrupting mycotoxin synthesis using a composition comprising vibrio gazogenes
发明人：CHANDA ANINDYA
权利人:Mycologics LLC
摘要:A method of inhibiting mycotoxin synthesis in filamentous fungi comprises contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC. Additionally, infections caused by filamentous fungi can be inhibited by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942. Endosomal function in filamentous fungi can be disrupted by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942. Hyphal fusion formation can be restricted in filamentous fungi by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942.

专利号:US-6947844-B2
优先权日:2000-08-09
标 题 :Modulators of ribosomal function and identification thereof
发明人：STEITZ THOMAS A; MOORE PETER B; BAN NENAD; NISSEN POUL; HANSEN JEFFREY
权利人:UNIV YALE
摘要:The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.

专利号:US-6952650-B2
优先权日:2001-08-03
标题:Modulators of ribosomal function and identification thereof
发明人：STEITZ THOMAS A; MOORE PETER B; BAN NENAD; NISSEN POUL; HANSEN JEFFREY
权利人:UNIV YALE
摘要:The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.

专利号:US-2015045422-A1
优先权日:2005-06-22
标题:Influenza treatment using targeted transient ribosomal inhibition
发明人：ZAMOYSKI MARK JOHN
权利人:ZAMOYSKI MARK JOHN
摘要:Novel methods are presented for treating Influenza by using Targeted Transient Ribosomal Inhibition (TTRI), with TTRI drugs administered by inhalation, to silence expression of every protein underlying the etiology and pathology of the influenza infection, and without adversely effecting normal cells in the lungs. The therapeutic effect is dual Antiviral and Anti-Inflammatory activity which is localized to the lungs. Pulmonary TTRI for influenza silences expression of all 10 influenza viral proteins and de novo synthesis of cytokines and leukotrienes produced in the lungs. By targeting ribosomes, TTRI is insensitive to viral mutations or human alterations to the virus. TTRI provides an off-the-shelf solution for preventing mortality from any strain of influenza.

专利号:US-11213031-B2
优先权日:2017-11-13
标 题:Tetrazolylpropyl derivatives and their use as fungicides
发明人：SUDAU ALEXANDER; HOFFMANN SEBASTIAN; DAHMEN PETER; WEBSTER ROBERT ALAN; MEISSNER RUTH; GOERTZ ANDREAS; MILLER RICARDA; COQUERON PIERRE-YVES; BERNIER DAVID; NICOLAS LIONEL; BRUNET STEPHANE; KENNEL PHILIPPE; TOQUIN VALERIE; GOURGUES MATHIEU; LOQUE DOMINIQUE; THOMAS VINCENT
权利人:BAYER AG; BAYER CROPSCIENCE AG
摘要:The present invention relates to tetrazolylpropyl derivatives of formula (I) n nwherein one of V 1 and V 2 represents CR 3 and the other one of V 1 and V 2 represents N, Q represents a 6-membered aromatic cycle as defined in the specification, and R 1 , R 2 , R 3 , R 4 , and R 5 are defined as disclosed in the specification, to compositions comprising such compounds, to the use of said compounds as fungicides, as well as to particular intermediates useful in the synthesis of said tetrazolylpropyl derivatives.