CAS: 1928-37-6; Methyl 2-(2,4,5-Trichlorophenoxy)Acetate
该化合物是淡黄色的无色液体,有独特的气味,因其在控制各种大叶杂草方面的效力而闻名,并经常用于农业用途;氯原子的存在增强了其除草特性,有助于其破坏植物生长过程的能力;甲基2,4,5-三氯氧氧乙酸酯在有机溶剂中具有中度溶解性,但在水中溶解性有限,影响其环境行为和生物利用率;鉴于该物质对非目标有机体的潜在毒性及其在环境中的持久性,必须谨慎地处理该物质;在应用该物质时,应注意采取安全措施,以尽量减少接触风险;
- 英文名称Methyl 2-(2,4,5-Trichlorophenoxy)Acetate
- 中文名称2-(2,4,5-三氯苯氧基)乙酸甲酯
- IUPAC名称methyl 2-(2,4,5-trichlorophenoxy)acetate
- 其它别名Aceticacid, (2,4,5-trichlorophenoxy)-, methyl ester (6CI,7CI,8CI,9CI); 2,4,5-T Methylester; 2,4,5-TME; 2,4,5-Trichlorophenoxyacetic acid methyl ester; Methyl(2,4,5-trichlorophenoxy)acetate
- CAS编号1928-37-6
- MFCD编号:MFCD00055247
- EINECS号:217-669-1
- FDA UNII编号:131049BJ6I
- 分子式:C9H7Cl3O3分子量:269.51
- 产品CID: 976282
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
1928-38-7 37785-57-2 358731-37-0物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07 & GHS09;
注释: Exclamation mark & Environment - 危险类别急性毒性 类别4(经口)
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P391-P403+P233-P405-P501
- 危险等级6.1(b)
- UN编号3345.0
- 危险品标志F,Xn,N
- 包装等级Ⅲ
- 安全声明36/37-61-62-60-24-16
- 危险类别码11-38-48/20-51/53-62-65-67-50/53-36/37/38-22-36
- WGK Germany3
欧盟法规
《欧盟PIC法规》ECHA物质ECHA物质OtherC&L通报REACH预注册上下游产品
CAS号93-76-5 2,4,5-涕 | CAS号74-88-4 碘甲烷 | CAS号95-95-4 2,4,5-三氯苯酚 | CAS号77-78-1 硫酸二甲酯 | CAS号2381-77-3 2-(2,4,5-三氯苯氧基)乙酰肼 | CAS号86745-94-0 diethyl-[2-[[2-... | CAS号86746-00-1 N-(2-morpholin-... | CAS号86746-01-2 N-(3-morpholin-... | CAS号86746-03-4 1-Methyl-4-((2,...合成工艺路线路线简述
- 合成目标产物 2,4,5-T-Methyl Ester 主要起始原料 2,4,5-Trichlorophenol
- (文献来源)合成步骤主要原料 2,4,5-Trichlorophenol
📜2,4,5-三氯苯酚置于sodium Hydroxide,Potassium Carbonate体系中,用 水,丙酮 用作溶剂,化学反应 11.25H,反应生成2,4,5-T 甲酯
参考文献:Basic Amides Of 2,4,5-Trichlorophenoxyacetic,2,4,6-Trimethylphenoxyacetic And 4-Bromo-3,5-Dimethylphenoxyacetic Acid And Some Related Compounds; Synthesis And Pharmacological Screening
标题:Basic Amides Of 2,4,5-Trichlorophenoxyacetic,2,4,6-Trimethylphenoxyacetic And 4-Bromo-3,5-Dimethylphenoxyacetic Acid And Some Related Compounds; Synthesis And Pharmacological Screening
摘要:甲酯类化合物 Ii 的反应与 2,4,5-三氯苯氧乙酸 (Ia),2,4,6-三甲基苯氧乙酸 (Ib) 和 4-溴-3,5-二甲基苯氧乙酸 (Ic) 在沸腾的乙醇中与 2-二乙胺基乙胺,2-吗啉基乙胺,3-吗啉基丙胺,1-甲基哌嗪,3-(4-甲基哌嗪基)丙胺,3-[4-(2-甲苯基)哌嗪]丙胺和 1,4-双(3-氨基丙基)哌嗪的反应产生了基本酰胺 Va-Xic,这些酰胺以盐酸盐的形式分离出来.酸氯化物 Iva 和 Ivb 与 1,4-双(2-羟乙基)哌嗪和 1,4-双(3-羟丙基)哌嗪在二甲基甲酰胺中的反应直接产生了双酯的二盐酸盐 Xiiab 和 Xiiiab.制备的化合物仅具有微弱的中枢神经系统效应(主要是抑制性的);它们具有局部麻醉,轻度降压(其中一些为肾上腺素受体拮抗剂),抗心律失常和外周血管扩张活性.
Doi:10.1135/cccc19831089
海关参考信息
- 2905310000-1,2-乙二醇
2908191000-对氯苯酚
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of 5-Membered Heterocycles And Related Compounds.作者:Vishnuji Ram,Hridvanand Pandey
摘要:Some 1-(2, 4-Dichlorophenoxy And 2, 4, 5-Trichlorophenoxy) Acetyl-4-Arylthiosemicarbazides Were Prepared From Corresponding Chlorophenoxyacetohydrazide. The Resulting Thiosemicarbazides Were Cyclised Into 1, 3, 4-Thiadiazoles And 5-Mercapto-1, 2, 4-Triazoles Under Different Reaction Conditions. The Mercapto Compounds Were Converted Into Sulphides And Sulphones. N'-Arylidene (2, 4-Dichlorophenoxy) Acetohydrazides And 5-Substituted-1, 3, 4-Oxadiazole-2-Thiones Were Also Prepared From (2, 4-Dichlorophenoxy And 2, 4, 5-Trichlorophenoxy) Acetohydrazides Separately And Were Subjected To Mannich Reaction. Some Of These Compounds Were Evaluated As Fungicides Against Aspergillus Niger.
合成参考文献
参考文献:10.1038/ncb3255
摘要:Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484–96.
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