CAS: 136705-62-9; (2R,5R)-1-[2-[(2R,5R)-2,5-Diethylphospholan-1-Yl]Ethyl]-2,5-Diethylphospholane

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上下游产品

1,2-diphosphinoethane (S,S)-°Ctane-3,6-diol cyclic sulfate (3S,6S)-°Ctane-3,6-diol

合成工艺路线路线简述

    📜(3S,6S)-3,6-辛二醇置于ruthenium Trichloride,Sodium Periodate,正丁基锂,氯化亚砜体系中,化学反应 5.5H,反应生成(+)-1,2-双[(2R,5R)-2,5-二乙基膦烷基]乙烷
    参考文献:Burk,Mark J.; Feaster,John E.; Nugent,William A.,Journal Of The American Chemical Society,1993,Vol. 115,# 22,P. 10125-10138
    标题:Burk,Mark J.; Feaster,John E.; Nugent,William A.,Journal Of The American Chemical Society,1993,Vol. 115,# 22,P. 10125-10138

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    专利信息


    专利号:US-9309165-B2
    优先权日:2012-12-19
    标 题 :6-chloro-3-(phenyl-d5)-inden-1-one and use thereof
    发明人:JACOBSEN MIKKEL FOG; BRANDES SEBASTIAN
    权利人:LUNDBECK & CO AS H
    摘要:The present invention discloses the compound 6-chloro-3-(phenyl-d 5 )-inden-1-one (I) and routes of synthesis to obtain (I). In a further aspect the present invention discloses the use of (I) for the synthesis of (S)-6-chloro-3-(phenyl-d 5 )-indan-1-one.

    专利号:AU-2005221401-A1
    优先权日:2004-03-12
    标题:C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

    专利号:US-2005228190-A1
    优先权日:2004-03-12
    标题:C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

    专利号:WO-2005087370-A1
    优先权日:2004-03-12
    标题:C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

    专利号:JP-2007528893-A
    优先权日:2004-03-12
    标 题:C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

    专利号:TW-I299990-B
    优先权日:2004-03-12
    标题 :C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Ojima, I.; Vu, A. T.; Bonafoux, D., Science of Synthesis, (2001) 1, 569.
    摘要:Gudat, D., Science of Synthesis, (2009) 42, 183.
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