CAS: 103-48-0; Phenethyl Isobutyrate

相似化合物

103-45-7 140-26-1 103-52-6

上下游产品

CAS号60-12-8 苯乙醇 | CAS号79-31-2 异丁酸 | CAS号97-62-1 2-甲基丙酸乙酯 | CAS号97-72-3 异丁酸酐 | CAS号39207-65-3 2-异丁酰环己酮 | CAS号111-29-5 1,5-戊二醇 | CAS号79-30-1 异丁酰氯 | CAS号71-43-2 苯 | CAS号43216-34-8 phenethyl 2-bro... | CAS号547-63-7 异丁酸甲酯 | CAS号60-12-8 苯乙醇

Phenethyl 2-Bromo-2-Methylpropanoate置于异丙醇,反式-二叔丁基连二次硝酸酯体系中,化学反应 5.0H,反应生成异丁酸苯乙酯
参考文献:Organic Reducing Agents: Some Radical Chain Reactions Of Ketyl And 1,3-Dioxolanyl Radicals With Activated Bromides
标题:Organic Reducing Agents: Some Radical Chain Reactions Of Ketyl And 1,3-Dioxolanyl Radicals With Activated Bromides
摘要:The Radical Chain Reduction Of Primary And Secondary Alpha-Bromo Esters By 2-Propanol And 2-Methyldioxolane Has Been Shown To Be A Kinetically Viable Process With Average Chain Lengths Of >10 At Temperatures Between 30 And 60 Degrees C. For Electron-Deficient Bromides,These Simple Organic Reagents May Effectively Replace The More Commonly Used (And More Expensive) Organosilicon Or Tin Hydides. Some Mechanistic Insights Have Been Obtained From A Combination Of Kinetic And Thermodynamic Measurements. The Rate Constants For The Reaction Of The 2-Hydroxy-2-Propyl And The 2-Methyl-1,3-Dioxolan-2-Yl Radicals With A Primary Bromo Ester Have Been Estimated To Be 8 X 10(3) M(-1) S(-1) And 6 X 10(3) M(-1) S(-1),Respectively,At 30 Degrees C In Acetonitrile. The Electrochemical Oxidation Potentials Of A Number Of Electron-Rich Radicals Derived From Hydrogen Atom Abstraction From Alcohols And Dioxolanes,Determined Using Photomodulation Voltammetry,Provide An Assessment Of The Thermochemisty Of The Putative Outer Sphere Electron-Transfer Reaction Between The Radical And The Alpha-Bromo Ester (The Value For 1,3-Dioxolane Has Been Redetermined And Corrects An Erroneous Value Previously Published). From These Data,It Is Shown That The Order Of Reactivity Of The Organic Reducing Agents Follows The Same Trend As The Oxidation Potentials Of The Corresponding Radicals. Rate Constants For The Outer Sphere Electron-Transfer Reduction Of The Bromo Esters By Electrochemically Generated Radical Anions Were Used To Establish A Marcus-Type Relationship Between The Rate Constants And The Standard Potential Of The Reducing Agent. Comparison Of These Rate Constants With Those For The Reactions Of The Electron-Rich Radicals Suggest That The Reactions Of The Methanol; And Ethanol-Derived Radicals Do Not Proceed Via Outer Sphere Electron Transfer As Had Been Previously Suggested But Have Significant Bonding (I.E.,Atom Transfer) Character At The Transition State. Electron Transfer In The Reactions Of The 2-Propanol-And 2-Methyl-1,3-Dioxolane-Derived Radicals Cannot Be Ruled Out. Nevertheless,The Order Of Reactivity Of The Organic Reducing Agents Follows The Same Trend As The Oxidation Potentials Of The Corresponding Radicals Suggesting That These Potentials Can Be Used As A Predictive Tool For The Design Of New Reagents.
Doi:10.1021/jo00095A050

专利信息

专利号:US-2008176857-A1
优先权日:2005-03-25
标题 :4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: n n n n n n n n n n wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2 , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2008200475-A1
优先权日:2005-03-28
标题:4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2a , R x , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2008194590-A1
优先权日:2005-03-28
标 题:4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , X 2k , R 2l , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-10647942-B2
优先权日:2016-12-22
标题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of undecavertol derivatives having unique and desired flavor and/or fragrant characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-12114681-B2
优先权日:2018-06-04
标题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; TANUMA KENJI
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-2021198229-A1
优先权日:2018-03-08
标 题 :Fragrance and flavor materials from 1-(2-hydroxy-4-methylcyclohexyl)-ethanone
发明人：DICKERSON THALIA S; LOMBARDO LOUIS J; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to 1-(2-hydroxy-4-methycyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients to modify or enhance already existing fragrance compositions, solvents, media, and the like.