CAS: 535-32-0; (R)-2-Amino-4-(Ethylthio)Butanoic Acid

相似化合物

67-21-0 13073-35-3 1396988-59-2

上下游产品

CAS号13073-47-7 S-benzyl-D-homo... | CAS号36506-17-9 4-ethylsulfanyl...

📜S-Benzyl-D-Homocysteine置于氨,Sodium体系中,化学反应生成 D-乙硫氨基酪酸
参考文献:Stekol; Weiss,Journal Of Biological Chemistry,1949,Vol. 179,P. 1050
标题:Stekol; Weiss,Journal Of Biological Chemistry,1949,Vol. 179,P. 1050

专利信息

专利号:US-9803180-B2
优先权日:2013-11-06
标 题 :S-adenosylmethionine (SAM) synthase variants for the synthesis of artificial cofactors
发明人：DIPPE MARTIN; BRANDT WOLFGANG; WESSJOHANN LUDGER A; ROST HANNES; PORZEL ANDREA
权利人:LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE STIFTUNG DES OFFENTLICHEN RECHTS; Leibniz-Institut für Pflanzenbiochemie Stiftung des öffentlichen Rechts
摘要:The present invention relates to isolated polypeptides that are derived from wildtype Bacillus subtilis S-Adenosylmethionine (SAM) synthase or from a biologically active fragment thereof, wherein said isolated polypeptides comprise an amino acid sequence that, in relation to the amino acid sequence of said wildtype Bacillus subtilis SAM synthase or of the biologically active fragment thereof, comprises at least one amino acid substitution, selected from the group consisting of amino acid substitutions at positions I317 and I105. The present invention further relates to respective isolated nucleic acids, vectors, host cells, uses and methods for the production of SAM derivatives.

专利号:US-5892038-A
优先权日:1997-12-08
标 题 :Hydroxy-amino acid amides
发明人：DOLLE III ROLAND ELLWOOD; PATEL HITESH K
权利人:PHARMACOPEIA INC
摘要:Compounds of Formula I I are disclosed as inhibitors of plasmepsin and cathepsin D. The compounds are therefore useful to treat diseases such as malaria. In preferred compounds of formula I, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or a substituted piperazinealkanoic acid. Intermediates in the solid phase synthesis of compounds of formula I, in which the compounds are attached to a solid support, are also disclosed.

专利号:US-2017240870-A9
优先权日:2013-11-06
标 题:S-adenosylmethionine (sam) synthase variants for the synthesis of artificial cofactors

专利号:EP-3066197-B1
优先权日:2013-11-06
标题:S-adenosylmethionine (sam) synthase variants for the synthesis of artificial cofactors

专利号:EP-3066197-A1
优先权日:2013-11-06
标题:S-adenosylmethionine (sam) synthase variants for the synthesis of artificial cofactors

专利号:US-5872262-A
优先权日:1996-11-05
标 题:Hydroxy-amino acid amides
发明人：DOLLE ROLAND ELLWOOD III; JOHNSON THEODORE O JR; TAO SHIWEI
权利人:PHARMACOPEIA INC
摘要:Compounds of Formula I I are disclosed as inhibitors of plasmepsin and cathepsin D. The compounds are therefore useful to treat diseases such as malaria. In preferred compounds of formula I, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or a substituted piperazinealkanoic acid. Intermediates in the solid phase synthesis of compounds of formula I, in which the compounds are attached to a solid support, are also disclosed.