CAS: 524-95-8; 2-((Diphenylboryl)Oxy)Ethanamine

该化合物是一种有机化合物,其特点是将原子弹原子结为两个苯基组和一个氨基乙氧组体,其特征是,它能够作为离子体,形成金属离子复合体,可用于各种化学应用,包括催化和材料科学;有机溶剂因其芳香结构,通常具有良好的溶解性,在标准条件下也有助于其稳定性;氨基化合物的存在允许与生物系统进行潜在互动,使其对药用化学感兴趣;此外,双乙基混合物可参与氢联结和协调化学,增强其再活性和功能;

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号856622-73-6 triphenylborane... | CAS号60-29-7 乙醚 | CAS号141-43-5 2-氨基乙醇 | CAS号108-86-1 溴苯 | CAS号4426-21-5 二苯基硼酸酐 | CAS号2622-89-1 diphenylborinic acid | CAS号23147-97-9 2-methylpropoxy... | CAS号15323-04-3 butoxy(diphenyl... | CAS号960-71-4 三苯基硼烷 | CAS号4426-21-5 二苯基硼酸酐 | CAS号14587-79-2 (SP-4-2)-dichlo... | CAS号11113-50-1 硼酸 | CAS号98-80-6 苯硼酸 | CAS号2622-89-1 diphenylborinic acid | CAS号5868-90-6 N-[(E)-(2,4-dic... | CAS号59911-25-0 (2-HYDROXYBENZA... | CAS号61733-90-2 2-bis(4-chlorop...

合成工艺路线路线简述

  • 合成目标产物 2-Aminoethoxydiphenyl Borate 主要起始原料 Diphenylborinic Anhydride And Monoethanolamine
  • (文献来源)合成步骤主要原料 Diphenylborinic Anhydride 和 Monoethanolamine
Phenylmagnesium Bromide 反应生成 二苯基酸
参考文献:Organoboron Compounds. Iv.1 Aminoethyl Diarylborinates
标题:Organoboron Compounds. Iv.1 Aminoethyl Diarylborinates
摘要:
DOI:10.1021/ja01614A039

海关参考信息

专利信息


专利号:US-2008311580-A1
优先权日:2004-03-09
标 题:Novel genes encoding proteins involved in proanthocyanidin synthesis
发明人:ABRAHAMS SHARON; ASHTON ANTHONY RICHARD; TANNER GREGORY JOHN; LARKIN PHILIP JOHN
权利人:COMMW SCIENT IND RES ORG
摘要:This inventions provides an isolated protein or polypeptide having activity in the synthesis of proanthocyanidin (PA) polymer from epicatechin or catechin in plants, and which is not naturally regulated by the TT2 or TT8 regulators, or a fragment comprising at least about 10 contiguous amino acids derived from said protein or polypeptide, particularly TDS1, TDS2, TDS3, TDS4, TDS5, or TDS6 protein, or fragment thereof. n Also provided are nucleic acid encoding such proteins or polypeptides; plant cells and plants containing and expressing such nucleic acids; antibodies that bind to such proteins or polypeptides; and related methods.

专利号:US-8318928-B2
优先权日:2008-12-15
标题 :Fused imidazole carboxamides as TRPV3 modulators
发明人:CHAUDHARI SACHIN SUNDARLAL; ABRAHAM THOMAS; KADAM ASHOK BHAUSAHEB; DHONE SACHIN VASANTRAO; KADAM SURESH MAHADEV; KHAIRATKAR-JOSHI NEELIMA; KATTIGE VIDYA GANAPATI
权利人:CHAUDHARI SACHIN SUNDARLAL; ABRAHAM THOMAS; KADAM ASHOK BHAUSAHEB; DHONE SACHIN VASANTRAO; KADAM SURESH MAHADEV; KHAIRATKAR-JOSHI NEELIMA; KATTIGE VIDYA GANAPATI; GLENMARK PHARMACEUTICALS SA
摘要:The present invention provides transient receptor potential vanilloid (TRPV) modulators of formula (I). In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPV3.

专利号:US-2011237659-A1
优先权日:2008-11-17
标题:Chromenone derivatives as trpv3 antagonists
发明人:CHAUDHARI SACHIN SUNDARLAL; THOMAS ABRAHAM; KADAM ASHOK BHAUSAHEB; DHONE SACHIN VASANTRAO; ADIK BHARAT GANGADHAR; KHAIRATKAR-JOSHI NEELIMA; KATTIGE VIDYA GANAPATI
权利人:GLENMARK PHARMACEUTICALS SA
摘要:The present invention provides transient receptor potential vanilloid (TRPV) modulators of formula (I). In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPV3.

专利号:EP-3925948-A1
优先权日:2019-04-26
标 题:Intermediate of eribulin, synthesis method therefor and use thereof

专利号:US-2022204523-A1
优先权日:2019-04-26
标 题 :Intermediate of eribulin and synthesis method and use thereof

专利号:WO-2020216034-A1
优先权日:2019-04-26
标 题:Intermediate of eribulin, synthesis method therefor and use thereof
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合成参考文献


参考文献:10.1016/j.ejphar.2011.06.025
摘要:Wolkowicz PE, Huang J, Umeda PK, Sharifov OF, Tabengwa E, Halloran BA, Urthaler F, Grenett HE. Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity. Eur J Pharmacol. 2011 Oct 01;668(1-2):208–16. doi: 10.1016/j.ejphar.2011.06.025.
参考文献:10.1007/s00232-011-9382-6
摘要:Nazıroğlu M, Özgül C, Çiğ B, Doğan S, Uğuz AC. Glutathione Modulates Ca2+ Influx and Oxidative Toxicity Through TRPM2 Channel in Rat Dorsal Root Ganglion Neurons. The Journal of Membrane Biology. 2011 Jul 12;242(3):109. doi: 10.1007/s00232-011-9382-6.
参考文献:10.1007/s00425-005-0167-y
摘要:Mahroug S, Courdavault V, Thiersault M, St-Pierre B, Burlat V. Epidermis is a pivotal site of at least four secondary metabolic pathways in Catharanthus roseus aerial organs. Planta. 2006 May;223(6):1191–200. doi: 10.1007/s00425-005-0167-y.
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